Genetic structure of the endangered milky stork (Mycteria cinerea) in Thailand with implications for captive breeding and reintroduction

Abstract Local extinction of milky stork Mycteria cinerea has been reported from the wild of Thailand. Only one captive population exists at Nakhon Ratchasima Zoo and is currently maintained as a breeding stock of the country. To initiate future reintroduction program, determination of genetic diver...

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Main Authors: Amporn Wiwegweaw, Damisa Kaminsin, Chitchai Chantangsi, Natapot Warrit, Nutthanun Khantasup, Saowaphang Sanannu, Wirongrong Changphet
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-10726-3
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author Amporn Wiwegweaw
Damisa Kaminsin
Chitchai Chantangsi
Natapot Warrit
Nutthanun Khantasup
Saowaphang Sanannu
Wirongrong Changphet
author_facet Amporn Wiwegweaw
Damisa Kaminsin
Chitchai Chantangsi
Natapot Warrit
Nutthanun Khantasup
Saowaphang Sanannu
Wirongrong Changphet
author_sort Amporn Wiwegweaw
collection DOAJ
description Abstract Local extinction of milky stork Mycteria cinerea has been reported from the wild of Thailand. Only one captive population exists at Nakhon Ratchasima Zoo and is currently maintained as a breeding stock of the country. To initiate future reintroduction program, determination of genetic diversity in this captive population is crucial for its long-term sustainability in nature. The present study employed a combination of maternally inherited mitochondrial control region and biparentally inherited nuclear microsatellite markers to evaluate genetic status of these captive individuals. Phylogenetic analysis and haplotype network construction demonstrated moderate haplotype diversity (h = 0.560 ± 0.050) and low nucleotide polymorphism (π = 0.0007 ± 0.0001). Multilocus microsatellite examination further showed low heterozygosity (H O = 0.387; H E = 0.374) with no significant evidence of inbreeding (F IS = -0.036). Moreover, STRUCTURE computation revealed two distinct genetic clusters among all studied individuals. Cluster 1 carried all three identified haplotypes and exhibited relatively higher genetic diversity than the cluster 2. Significant inbreeding was not observed in these two clusters. Assessment of pairwise relatedness additionally indicated that a majority of sample pairs were not genealogically related, thereby providing potential candidates for future breeding. Finally, suitable stork individuals and criteria for the effective selection of breeding pairs are proposed. Our research not only reports comprehensive genetic data of the sole remaining population of Thai milky stork for the first time, but also proposes a practical strategic framework by utilizing the obtained genetic information along with judicious breeding selection for recovering this endangered species of Thailand.
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spelling doaj-art-395839f4bf904edcb37aabc620b3196f2025-08-20T04:01:51ZengNature PortfolioScientific Reports2045-23222025-07-0115111310.1038/s41598-025-10726-3Genetic structure of the endangered milky stork (Mycteria cinerea) in Thailand with implications for captive breeding and reintroductionAmporn Wiwegweaw0Damisa Kaminsin1Chitchai Chantangsi2Natapot Warrit3Nutthanun Khantasup4Saowaphang Sanannu5Wirongrong Changphet6Population and Conservation Genetics Laboratory, Department of Biology, Faculty of Science, Chulalongkorn UniversityPopulation and Conservation Genetics Laboratory, Department of Biology, Faculty of Science, Chulalongkorn UniversityDepartment of Biology, Faculty of Science, Chulalongkorn UniversityCenter of Excellence in Entomology and Department of Biology, Faculty of Science, Chulalongkorn UniversityPopulation and Conservation Genetics Laboratory, Department of Biology, Faculty of Science, Chulalongkorn UniversityAnimal Conservation and Research Institute, The Zoological Park Organization of ThailandConservation, Research and Animal Health, Department of Nakhon Ratchasima Zoo, The Zoological Park Organization of ThailandAbstract Local extinction of milky stork Mycteria cinerea has been reported from the wild of Thailand. Only one captive population exists at Nakhon Ratchasima Zoo and is currently maintained as a breeding stock of the country. To initiate future reintroduction program, determination of genetic diversity in this captive population is crucial for its long-term sustainability in nature. The present study employed a combination of maternally inherited mitochondrial control region and biparentally inherited nuclear microsatellite markers to evaluate genetic status of these captive individuals. Phylogenetic analysis and haplotype network construction demonstrated moderate haplotype diversity (h = 0.560 ± 0.050) and low nucleotide polymorphism (π = 0.0007 ± 0.0001). Multilocus microsatellite examination further showed low heterozygosity (H O = 0.387; H E = 0.374) with no significant evidence of inbreeding (F IS = -0.036). Moreover, STRUCTURE computation revealed two distinct genetic clusters among all studied individuals. Cluster 1 carried all three identified haplotypes and exhibited relatively higher genetic diversity than the cluster 2. Significant inbreeding was not observed in these two clusters. Assessment of pairwise relatedness additionally indicated that a majority of sample pairs were not genealogically related, thereby providing potential candidates for future breeding. Finally, suitable stork individuals and criteria for the effective selection of breeding pairs are proposed. Our research not only reports comprehensive genetic data of the sole remaining population of Thai milky stork for the first time, but also proposes a practical strategic framework by utilizing the obtained genetic information along with judicious breeding selection for recovering this endangered species of Thailand.https://doi.org/10.1038/s41598-025-10726-3ConservationD-loopGenetic diversityMicrosatellite polymorphismWading birds
spellingShingle Amporn Wiwegweaw
Damisa Kaminsin
Chitchai Chantangsi
Natapot Warrit
Nutthanun Khantasup
Saowaphang Sanannu
Wirongrong Changphet
Genetic structure of the endangered milky stork (Mycteria cinerea) in Thailand with implications for captive breeding and reintroduction
Scientific Reports
Conservation
D-loop
Genetic diversity
Microsatellite polymorphism
Wading birds
title Genetic structure of the endangered milky stork (Mycteria cinerea) in Thailand with implications for captive breeding and reintroduction
title_full Genetic structure of the endangered milky stork (Mycteria cinerea) in Thailand with implications for captive breeding and reintroduction
title_fullStr Genetic structure of the endangered milky stork (Mycteria cinerea) in Thailand with implications for captive breeding and reintroduction
title_full_unstemmed Genetic structure of the endangered milky stork (Mycteria cinerea) in Thailand with implications for captive breeding and reintroduction
title_short Genetic structure of the endangered milky stork (Mycteria cinerea) in Thailand with implications for captive breeding and reintroduction
title_sort genetic structure of the endangered milky stork mycteria cinerea in thailand with implications for captive breeding and reintroduction
topic Conservation
D-loop
Genetic diversity
Microsatellite polymorphism
Wading birds
url https://doi.org/10.1038/s41598-025-10726-3
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