Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy

Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy

The amyloid cascade hypothesis posits that amyloid-β oligomers (AβOs) are the most neurotoxic species in Alzheimer’s disease (AD). These oligomers, characterized by their high β-sheet content, have been shown to significantly disrupt cell membranes, induce local inflammation, and impair autophagy pr...

Full description

Saved in:
Bibliographic Details
Main Authors: Shiwani Randhawa, Trilok Chand Saini, Manik Bathla, Rahul Bhardwaj, Rubina Dhiman, Amitabha Acharya
Format: Article
Language:English
Published: Beilstein-Institut 2025-04-01
Series:Beilstein Journal of Nanotechnology
Subjects:
alzheimer’s disease
amyloid
amyloid-β oligomers
detection
dissociation
nanomaterials
Online Access:https://doi.org/10.3762/bjnano.16.44
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items