Pentalogy of Cantrell. A stillbirth case report

Introduction: Pentalogy of Cantrell is a rare congenital disorder characterized by midline birth anomalies. Its embryological origins are related to anomalies of the abdominal wall that prevent the closure of the thorax. Its etiology is not yet clear, but it has been associated with a failure of mi...

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Main Authors: Maribel Palencia Palacios, Blanca Viviana Fajardo Idrobo, Valentina López Mosquera, Jaime Antonio Álvarez Soler
Format: Article
Language:English
Published: Universidad Nacional de Colombia 2022-08-01
Series:Case Reports
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Online Access:https://revistas.unal.edu.co/index.php/care/article/view/91323
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author Maribel Palencia Palacios
Blanca Viviana Fajardo Idrobo
Valentina López Mosquera
Jaime Antonio Álvarez Soler
author_facet Maribel Palencia Palacios
Blanca Viviana Fajardo Idrobo
Valentina López Mosquera
Jaime Antonio Álvarez Soler
author_sort Maribel Palencia Palacios
collection DOAJ
description Introduction: Pentalogy of Cantrell is a rare congenital disorder characterized by midline birth anomalies. Its embryological origins are related to anomalies of the abdominal wall that prevent the closure of the thorax. Its etiology is not yet clear, but it has been associated with a failure of migration of the lateral plate mesoderm to the midline. Case description: A stillbirth at 25.2 weeks of gestation diagnosed with pentalogy of Cantrell. The mother was a 14-year-old teenager with no relevant history of disease. An obstetric ultrasound was performed at 19 weeks of gestation and revealed findings suggestive of pentalogy of Cantrell. The mother was informed of the potential risks and future complications for the fetus, yet she chose to continue with the pregnancy. At 25.2 weeks of gestation, the mother went to the emergency department due to pain in the hypogastrium accompanied by moderate vaginal bleeding and absence of fetal activity. Once fetal death was confirmed by ultrasound, labor was induced, resulting in stillbirth with anencephaly, thoracic hypoplasia, gastroschisis, and eventration of the liver. Conclusions: Adequate antenatal care, including strict ultrasound follow-up, is essential to detect future complications in the fetus; to provide advice on possible malformations incompatible with life, such as pentalogy of Cantrell; and to determine the best therapeutic approach.
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spelling doaj-art-3947c85becf240afaaa3f36d8f8b973d2025-08-20T01:52:44ZengUniversidad Nacional de ColombiaCase Reports2462-85222022-08-018110.15446/cr.v8n1.91323Pentalogy of Cantrell. A stillbirth case reportMaribel Palencia Palacios0https://orcid.org/0000-0003-3408-4591Blanca Viviana Fajardo Idrobo1https://orcid.org/0000-0002-7515-6531Valentina López Mosquera2https://orcid.org/0000-0002-3198-4925Jaime Antonio Álvarez Soler3https://orcid.org/0000-0002-0581-4543Universidad del CaucaUniversidad del CaucaUniversidad del CaucaUniversidad del Cauca Introduction: Pentalogy of Cantrell is a rare congenital disorder characterized by midline birth anomalies. Its embryological origins are related to anomalies of the abdominal wall that prevent the closure of the thorax. Its etiology is not yet clear, but it has been associated with a failure of migration of the lateral plate mesoderm to the midline. Case description: A stillbirth at 25.2 weeks of gestation diagnosed with pentalogy of Cantrell. The mother was a 14-year-old teenager with no relevant history of disease. An obstetric ultrasound was performed at 19 weeks of gestation and revealed findings suggestive of pentalogy of Cantrell. The mother was informed of the potential risks and future complications for the fetus, yet she chose to continue with the pregnancy. At 25.2 weeks of gestation, the mother went to the emergency department due to pain in the hypogastrium accompanied by moderate vaginal bleeding and absence of fetal activity. Once fetal death was confirmed by ultrasound, labor was induced, resulting in stillbirth with anencephaly, thoracic hypoplasia, gastroschisis, and eventration of the liver. Conclusions: Adequate antenatal care, including strict ultrasound follow-up, is essential to detect future complications in the fetus; to provide advice on possible malformations incompatible with life, such as pentalogy of Cantrell; and to determine the best therapeutic approach. https://revistas.unal.edu.co/index.php/care/article/view/91323Pentalogy of CantrellMesodermGastroschisis
spellingShingle Maribel Palencia Palacios
Blanca Viviana Fajardo Idrobo
Valentina López Mosquera
Jaime Antonio Álvarez Soler
Pentalogy of Cantrell. A stillbirth case report
Case Reports
Pentalogy of Cantrell
Mesoderm
Gastroschisis
title Pentalogy of Cantrell. A stillbirth case report
title_full Pentalogy of Cantrell. A stillbirth case report
title_fullStr Pentalogy of Cantrell. A stillbirth case report
title_full_unstemmed Pentalogy of Cantrell. A stillbirth case report
title_short Pentalogy of Cantrell. A stillbirth case report
title_sort pentalogy of cantrell a stillbirth case report
topic Pentalogy of Cantrell
Mesoderm
Gastroschisis
url https://revistas.unal.edu.co/index.php/care/article/view/91323
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