Transcription factor NFKB1 mediates TUBB6 to promote the proliferation and suppress apoptosis in glioma via Wnt/β-catenin signaling pathway

Transcription factor NFKB1 mediates TUBB6 to promote the proliferation and suppress apoptosis in glioma via Wnt/β-catenin signaling pathway

Abstract Glioma remains one of the most challenging brain tumors with poor prognosis. In this study, we aimed to elucidate the role of TUBB6 in glioma and its potential as a diagnostic and prognostic biomarker. Analysis of the GSE42656 and TCGA datasets revealed that TUBB6 was significantly upregula...

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Bibliographic Details
Main Authors: Yan Li, Ziyu Shao, Jun Jiang, Hongyan Wang, Mei Zhang
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Oncology
Subjects:
TUBB6
Glioma
NFKB1
Apoptosis
Wnt/β-catenin signaling
Prognosis
Online Access:https://doi.org/10.1007/s12672-025-02268-x
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