Multiomics unravels the complexity of male obesity: a prospective observational study

Multiomics unravels the complexity of male obesity: a prospective observational study

Abstract Background Obesity is associated with varying degrees of metabolic dysfunction. In this study, we aimed to discover markers of the severity of metabolic impairment in men with obesity via a multiomics approach. Methods Thirty-two morbidly men with obesity who were candidates for Roux-en-Y g...

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Main Authors: Georgios E. Papadakis, Lucie Favre, Yassine Zouaghi, Nathalie Vionnet, Nicolas J. Niederländer, Michela Adamo, James S. Acierno, Dassine Berdous, Alexia Boizot, Jenny Meylan, Julijana Ivanisevic, Emmanuelle Paccou, Hector Gallart-Ayala, Tim Reyns, Elise Van Caeneghem, Bruno Lapauw, Jérôme Pasquier, Yasser Aleman, Styliani Mantziari, Olivier Salamin, Raul Nicoli, Tiia Kuuranne, Tom Fiers, Patric Hagmann, Federico Santoni, Andrea Messina, Nelly Pitteloud
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Translational Medicine
Subjects:
Male obesity
Metabolic risk stratification
Hypogonadism
Bariatric surgery
Transcriptomics
Online Access:https://doi.org/10.1186/s12967-024-06040-7
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