Endoscopic Biopsy Assessment of Neoplastic Prevalence in Dogs with Chronic Diarrhoea and Non-Suggestive Ultrasound Findings

Chronic diarrhoea is a frequent complaint in dogs. Abdominal ultrasonography is frequently utilised in cases of dogs with chronic diarrhoea. The prevalence of neoplasia in dogs with chronic diarrhoea for which ultrasonographic findings are not suggestive of neoplasia has not been reported. This stud...

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Main Authors: Ico Jolly-Frahija, Sophie Dormon, Hannah Shing, Ferran Valls Sanchez
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Sci
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Online Access:https://www.mdpi.com/2413-4155/7/2/39
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author Ico Jolly-Frahija
Sophie Dormon
Hannah Shing
Ferran Valls Sanchez
author_facet Ico Jolly-Frahija
Sophie Dormon
Hannah Shing
Ferran Valls Sanchez
author_sort Ico Jolly-Frahija
collection DOAJ
description Chronic diarrhoea is a frequent complaint in dogs. Abdominal ultrasonography is frequently utilised in cases of dogs with chronic diarrhoea. The prevalence of neoplasia in dogs with chronic diarrhoea for which ultrasonographic findings are not suggestive of neoplasia has not been reported. This study aimed to list the histologic diagnosis of endoscopic gastroduodenal biopsies in this specific population. The medical records of 115 dogs with chronic diarrhoea for which an abdominal ultrasound was not suggestive of a neoplastic process and had undergone endoscopic biopsies were reviewed. Cases were excluded if an abdominal ultrasound revealed a focal intestinal mass, loss of intestinal wall layering, or a mass lesion in another location. Dogs that had undergone previous treatment with immunosuppressants were also excluded. Histologic findings revealed neoplastic features in 3 out of 115 cases (2.6%) and non-neoplastic conditions in 112 cases (97.4%). In conclusion, the prevalence of neoplastic disease in this population was very low. This is valuable information when considering the diagnostic approach in patients which meet the population criteria and which would historically have had endoscopy and biopsy recommended with the main goal of excluding neoplasia but have moderate–high anaesthetic risk, limited access to endoscopy and/or when financial constraints are present (Figure 1).
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spelling doaj-art-38f197b0526445ac88ebbf26f092eabf2025-08-20T03:27:22ZengMDPI AGSci2413-41552025-03-01723910.3390/sci7020039Endoscopic Biopsy Assessment of Neoplastic Prevalence in Dogs with Chronic Diarrhoea and Non-Suggestive Ultrasound FindingsIco Jolly-Frahija0Sophie Dormon1Hannah Shing2Ferran Valls Sanchez3DWR Veterinary Specialists, Station Farm, London Road, Six Mile Bottom, Cambridgeshire CB8 0UH, UKAnderson Moores Veterinary Specialists, The Granary, Bunstead Barns, Poles Ln, Winchester SO21 2LL, UKSASH-Small Animal Specialist Hospital North Ryde, Sidney, NSW 2113, AustraliaWeYouVets, 85, Brentwood Road, Ingrave, Essex CM13 3NU, UKChronic diarrhoea is a frequent complaint in dogs. Abdominal ultrasonography is frequently utilised in cases of dogs with chronic diarrhoea. The prevalence of neoplasia in dogs with chronic diarrhoea for which ultrasonographic findings are not suggestive of neoplasia has not been reported. This study aimed to list the histologic diagnosis of endoscopic gastroduodenal biopsies in this specific population. The medical records of 115 dogs with chronic diarrhoea for which an abdominal ultrasound was not suggestive of a neoplastic process and had undergone endoscopic biopsies were reviewed. Cases were excluded if an abdominal ultrasound revealed a focal intestinal mass, loss of intestinal wall layering, or a mass lesion in another location. Dogs that had undergone previous treatment with immunosuppressants were also excluded. Histologic findings revealed neoplastic features in 3 out of 115 cases (2.6%) and non-neoplastic conditions in 112 cases (97.4%). In conclusion, the prevalence of neoplastic disease in this population was very low. This is valuable information when considering the diagnostic approach in patients which meet the population criteria and which would historically have had endoscopy and biopsy recommended with the main goal of excluding neoplasia but have moderate–high anaesthetic risk, limited access to endoscopy and/or when financial constraints are present (Figure 1).https://www.mdpi.com/2413-4155/7/2/39dogdiarrhoeaendoscopyabdominal ultrasonographyenteropathylymphoma
spellingShingle Ico Jolly-Frahija
Sophie Dormon
Hannah Shing
Ferran Valls Sanchez
Endoscopic Biopsy Assessment of Neoplastic Prevalence in Dogs with Chronic Diarrhoea and Non-Suggestive Ultrasound Findings
Sci
dog
diarrhoea
endoscopy
abdominal ultrasonography
enteropathy
lymphoma
title Endoscopic Biopsy Assessment of Neoplastic Prevalence in Dogs with Chronic Diarrhoea and Non-Suggestive Ultrasound Findings
title_full Endoscopic Biopsy Assessment of Neoplastic Prevalence in Dogs with Chronic Diarrhoea and Non-Suggestive Ultrasound Findings
title_fullStr Endoscopic Biopsy Assessment of Neoplastic Prevalence in Dogs with Chronic Diarrhoea and Non-Suggestive Ultrasound Findings
title_full_unstemmed Endoscopic Biopsy Assessment of Neoplastic Prevalence in Dogs with Chronic Diarrhoea and Non-Suggestive Ultrasound Findings
title_short Endoscopic Biopsy Assessment of Neoplastic Prevalence in Dogs with Chronic Diarrhoea and Non-Suggestive Ultrasound Findings
title_sort endoscopic biopsy assessment of neoplastic prevalence in dogs with chronic diarrhoea and non suggestive ultrasound findings
topic dog
diarrhoea
endoscopy
abdominal ultrasonography
enteropathy
lymphoma
url https://www.mdpi.com/2413-4155/7/2/39
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AT sophiedormon endoscopicbiopsyassessmentofneoplasticprevalenceindogswithchronicdiarrhoeaandnonsuggestiveultrasoundfindings
AT hannahshing endoscopicbiopsyassessmentofneoplasticprevalenceindogswithchronicdiarrhoeaandnonsuggestiveultrasoundfindings
AT ferranvallssanchez endoscopicbiopsyassessmentofneoplasticprevalenceindogswithchronicdiarrhoeaandnonsuggestiveultrasoundfindings