Investigation of <i>Atraphaxis virgata</i>, an Unexplored Medicinal Plant Rich in Flavonoids, as a Functional Material
Plants of the genus <i>Atraphaxis</i> have been widely used as traditional herbal medicines and are just beginning to be recognized for their pharmacological activities by scientific validation. In particular, <i>Atraphaxis virgata</i> (Regel) Krasn. has not reported even fun...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
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| Series: | Horticulturae |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2311-7524/11/1/70 |
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| Summary: | Plants of the genus <i>Atraphaxis</i> have been widely used as traditional herbal medicines and are just beginning to be recognized for their pharmacological activities by scientific validation. In particular, <i>Atraphaxis virgata</i> (Regel) Krasn. has not reported even fundamental data, such as antioxidant activity and phytochemical properties, which requires investigation for its medical application. In this study, phytochemical compounds of <i>A. virgata</i> extracts were identified using high-performance liquid chromatography (HPLC) and gas chromatography–mass spectrometry (GC-MS) and their antioxidant activity was evaluated. As a result, <i>A. virgata</i> extracts were analyzed using HPLC and found to contain hesperidin 13.18 mg/g-extract, rutin 4.49 mg/g-extract, catechin 3.23 mg/g-extract, gallic acid 2.93 mg/g-extract, epicatechin-3-gallate 1.28 mg/g-extract, kaempferol 0.26 mg/g-extract, and luteolin 0.09 mg/g-extract. Furthermore, GC-MS analysis detected nine compounds (e.g., lup-20(29)-en-3-one and decane) in the extracts, which were reported to have various biological activities. The ABTS IC<sub>50</sub>, DPPH IC<sub>50</sub>, and FRAP values of <i>A. virgata</i> extracts were determined to be 126.57 ± 0.24 μg/mL, 42.17 ± 1.14 μg/mL, and 122.59 ± 8.79 mmol/L, respectively. This study is the first to report the antioxidant activity of <i>A. virgata</i>, suggesting its potential as a functional food or medicinal material. |
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| ISSN: | 2311-7524 |