Intravitreal tPA Injection and Pneumatic Displacement for Submacular Hemorrhage in a 10-Year-Old Child

Background. Submacular hemorrhage can occur after blunt trauma to the eye. Intravitreal tissue plasminogen activator (tPA) and gas injection are often used for treatment and are effective for submacular hemorrhage caused by age-related macular degeneration. This report describes the clinical outcome...

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Main Authors: Takayuki Tsuyama, Hiroshi Hirose, Tomohiro Hattori
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2016/9809583
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author Takayuki Tsuyama
Hiroshi Hirose
Tomohiro Hattori
author_facet Takayuki Tsuyama
Hiroshi Hirose
Tomohiro Hattori
author_sort Takayuki Tsuyama
collection DOAJ
description Background. Submacular hemorrhage can occur after blunt trauma to the eye. Intravitreal tissue plasminogen activator (tPA) and gas injection are often used for treatment and are effective for submacular hemorrhage caused by age-related macular degeneration. This report describes the clinical outcome in a child with submacular hemorrhage caused by traumatic choroidal rupture who underwent successful intravitreal tPA injection and pneumatic displacement. Case Presentation. A 10-year-old boy developed sudden decrease of vision and a central scotoma in his right eye after trauma. Submacular hemorrhage was found in the eye. Visual acuity was 20/70 OD. Tissue plasminogen activator (12.5 μg in 0.05 mL) and 0.3 mL of pure sulfur hexafluoride were injected into the vitreous cavity under general anesthesia. After surgery, the patient was instructed to maintain a prone position. Displacement of the submacular hemorrhage from the fovea revealed a choroidal rupture, presumed to be the cause of the hemorrhage. After 4 months of follow-up, visual acuity was restored and final visual acuity is 20/16. Conclusion. Intravitreal tPA and gas injection can be an effective treatment for children with submacular hemorrhage.
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spelling doaj-art-38c76bd2109a4e938b3e2107ce2385982025-08-20T03:55:11ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302016-01-01201610.1155/2016/98095839809583Intravitreal tPA Injection and Pneumatic Displacement for Submacular Hemorrhage in a 10-Year-Old ChildTakayuki Tsuyama0Hiroshi Hirose1Tomohiro Hattori2Department of Ophthalmology, National Hospital Organization Nagoya Medical Center, 4-1-1 Sannomaru, Nakaku, Nagoya, Aichi 460-0001, JapanDepartment of Ophthalmology, National Hospital Organization Nagoya Medical Center, 4-1-1 Sannomaru, Nakaku, Nagoya, Aichi 460-0001, JapanDepartment of Ophthalmology, National Hospital Organization Nagoya Medical Center, 4-1-1 Sannomaru, Nakaku, Nagoya, Aichi 460-0001, JapanBackground. Submacular hemorrhage can occur after blunt trauma to the eye. Intravitreal tissue plasminogen activator (tPA) and gas injection are often used for treatment and are effective for submacular hemorrhage caused by age-related macular degeneration. This report describes the clinical outcome in a child with submacular hemorrhage caused by traumatic choroidal rupture who underwent successful intravitreal tPA injection and pneumatic displacement. Case Presentation. A 10-year-old boy developed sudden decrease of vision and a central scotoma in his right eye after trauma. Submacular hemorrhage was found in the eye. Visual acuity was 20/70 OD. Tissue plasminogen activator (12.5 μg in 0.05 mL) and 0.3 mL of pure sulfur hexafluoride were injected into the vitreous cavity under general anesthesia. After surgery, the patient was instructed to maintain a prone position. Displacement of the submacular hemorrhage from the fovea revealed a choroidal rupture, presumed to be the cause of the hemorrhage. After 4 months of follow-up, visual acuity was restored and final visual acuity is 20/16. Conclusion. Intravitreal tPA and gas injection can be an effective treatment for children with submacular hemorrhage.http://dx.doi.org/10.1155/2016/9809583
spellingShingle Takayuki Tsuyama
Hiroshi Hirose
Tomohiro Hattori
Intravitreal tPA Injection and Pneumatic Displacement for Submacular Hemorrhage in a 10-Year-Old Child
Case Reports in Ophthalmological Medicine
title Intravitreal tPA Injection and Pneumatic Displacement for Submacular Hemorrhage in a 10-Year-Old Child
title_full Intravitreal tPA Injection and Pneumatic Displacement for Submacular Hemorrhage in a 10-Year-Old Child
title_fullStr Intravitreal tPA Injection and Pneumatic Displacement for Submacular Hemorrhage in a 10-Year-Old Child
title_full_unstemmed Intravitreal tPA Injection and Pneumatic Displacement for Submacular Hemorrhage in a 10-Year-Old Child
title_short Intravitreal tPA Injection and Pneumatic Displacement for Submacular Hemorrhage in a 10-Year-Old Child
title_sort intravitreal tpa injection and pneumatic displacement for submacular hemorrhage in a 10 year old child
url http://dx.doi.org/10.1155/2016/9809583
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AT tomohirohattori intravitrealtpainjectionandpneumaticdisplacementforsubmacularhemorrhageina10yearoldchild