Visualization of HSP70-regulated mild-photothermal therapy for synergistic tumor treatment: a precise space-time mild-temperature photothermal ablation strategy

Visualization of HSP70-regulated mild-photothermal therapy for synergistic tumor treatment: a precise space-time mild-temperature photothermal ablation strategy

Abstract Mild-temperature photothermal therapy (MPTT) advances anticancer management by regulating reactive oxygen species (ROS) and lipid peroxides (LPO) to inhibit the overexpression of heat shock protein 70 (HSP70), thus decreasing the cellular heat resistance and increasing the efficacy of tumor...

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Bibliographic Details
Main Authors: Binyue Zhang, Yanchun Ma, Qi Liu, Shutong Wu, Lin Chen, Chunmei Jiang, Haonan Chen, Hongyan Jia, Ziliang Zheng, Ruiping Zhang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Nanobiotechnology
Subjects:
Dual-modal imaging
Ratiometric photoacoustic imaging
Second near-infrared window
Mild-photothermal therapy
Breast cancer
Online Access:https://doi.org/10.1186/s12951-025-03379-x
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