Prevalence of and Risk Factors for Dry Eye Symptom in Mainland China: A Systematic Review and Meta-Analysis

Purpose. To evaluate the pooled prevalence rate and risk factors of dry eye symptoms (DES) in mainland China. Methods. All the published population-based studies investigating the prevalence of DES in China were searched and evaluated against inclusion criteria. A systematic review and meta-analysis...

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Main Authors: Ning-ning Liu, Lei Liu, Jun Li, Yi-zhou Sun
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2014/748654
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author Ning-ning Liu
Lei Liu
Jun Li
Yi-zhou Sun
author_facet Ning-ning Liu
Lei Liu
Jun Li
Yi-zhou Sun
author_sort Ning-ning Liu
collection DOAJ
description Purpose. To evaluate the pooled prevalence rate and risk factors of dry eye symptoms (DES) in mainland China. Methods. All the published population-based studies investigating the prevalence of DES in China were searched and evaluated against inclusion criteria. A systematic review and meta-analysis were performed. Results. Twelve out of the 119 identified studies were included in the meta-analysis. The pooled prevalence of DES in China was 17.0%. Female individuals, subjects living in the Northern and Western China, and over 60 years of age had significantly higher prevalent rates (21.6%, 17.9%, 31.3%, and 34.4%, resp.) compared with their counterparts. Patients with diabetes were also found to be more vulnerable to DES. Conclusions. The pooled prevalence rate of DES in mainland China was lower than that in other Asian regions and countries. A remarkable discrepancy in the prevalence in different geographic regions was noted. Aging, female gender, and diabetes were found to be risk factors for DES in China.
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spelling doaj-art-38bc233179c84f2d99acd67f6245fdaa2025-08-20T03:55:11ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/748654748654Prevalence of and Risk Factors for Dry Eye Symptom in Mainland China: A Systematic Review and Meta-AnalysisNing-ning Liu0Lei Liu1Jun Li2Yi-zhou Sun3The Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, ChinaThe Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, ChinaThe Department of Cardiovascular Ultrasound, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, ChinaThe Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, ChinaPurpose. To evaluate the pooled prevalence rate and risk factors of dry eye symptoms (DES) in mainland China. Methods. All the published population-based studies investigating the prevalence of DES in China were searched and evaluated against inclusion criteria. A systematic review and meta-analysis were performed. Results. Twelve out of the 119 identified studies were included in the meta-analysis. The pooled prevalence of DES in China was 17.0%. Female individuals, subjects living in the Northern and Western China, and over 60 years of age had significantly higher prevalent rates (21.6%, 17.9%, 31.3%, and 34.4%, resp.) compared with their counterparts. Patients with diabetes were also found to be more vulnerable to DES. Conclusions. The pooled prevalence rate of DES in mainland China was lower than that in other Asian regions and countries. A remarkable discrepancy in the prevalence in different geographic regions was noted. Aging, female gender, and diabetes were found to be risk factors for DES in China.http://dx.doi.org/10.1155/2014/748654
spellingShingle Ning-ning Liu
Lei Liu
Jun Li
Yi-zhou Sun
Prevalence of and Risk Factors for Dry Eye Symptom in Mainland China: A Systematic Review and Meta-Analysis
Journal of Ophthalmology
title Prevalence of and Risk Factors for Dry Eye Symptom in Mainland China: A Systematic Review and Meta-Analysis
title_full Prevalence of and Risk Factors for Dry Eye Symptom in Mainland China: A Systematic Review and Meta-Analysis
title_fullStr Prevalence of and Risk Factors for Dry Eye Symptom in Mainland China: A Systematic Review and Meta-Analysis
title_full_unstemmed Prevalence of and Risk Factors for Dry Eye Symptom in Mainland China: A Systematic Review and Meta-Analysis
title_short Prevalence of and Risk Factors for Dry Eye Symptom in Mainland China: A Systematic Review and Meta-Analysis
title_sort prevalence of and risk factors for dry eye symptom in mainland china a systematic review and meta analysis
url http://dx.doi.org/10.1155/2014/748654
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