A preclinical model of peripheral T‐cell lymphoma GATA3 reveals DNA damage response pathway vulnerability
Abstract Peripheral T‐cell lymphoma (PTCL) represents a rare group of heterogeneous diseases in urgent need of effective treatments. A scarcity of disease‐relevant preclinical models hinders research advances. Here, we isolated a novel mouse (m)PTCL by serially transplanting a lymphoma from a germin...
Saved in:
| Main Authors: | Elizabeth A Kuczynski, Giulia Morlino, Alison Peter, Anna M L Coenen‐Stass, Jennifer I Moss, Neha Wali, Oona Delpuech, Avinash Reddy, Anisha Solanki, Charles Sinclair, Dinis P Calado, Larissa S Carnevalli |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2022-05-01
|
| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.202215816 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Emerging Role of Circulating T Follicular Helper Cells in Dengue Virus Immunity: Balancing Protection and Pathogenesis
by: Paola N. Flores-Pérez, et al.
Published: (2025-04-01) -
AhR agonist tapinarof ameliorates lupus autoimmunity by suppressing Tfh cell differentiation via regulation of the JAK2‐STAT3 signaling pathway
by: Ying Zhang, et al.
Published: (2023-06-01) -
Apolipoprotein A-I mediates function of follicular regulatory T cells and type 2 follicular helper T in allergic rhinitis
by: Xiangqian Qiu, MD, et al.
Published: (2025-04-01) -
Mechanism of biliary atresia caused by T follicular helper cells-induced immune injury
by: Ze Ji, et al.
Published: (2024-10-01) -
Pathogenesis of Autoimmunity/Systemic Lupus Erythematosus (SLE)
by: Shunichi Shiozawa
Published: (2025-07-01)