Programmed Death-Ligand 1, C-reactive Protein, and Neutrophil/Lymphocyte Ratio as Lymphangiogenesis Markers of Metastasis in Penile Cancer – A Systematic Review

The spread of penile cancer cells through lymphatic vessels provides the potential for using compounds involved in lymphangiogenesis, such as programmed death-ligand 1 (PD-L1), C-reactive protein (CRP), neutrophil/lymphocyte ratio (NLR), and Ki-67, in predicting the development of lymphatic metastas...

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Main Authors: Yudiana I Wayan, Marta Stacia Novia, Sugianto Ronald, Lestari Anak Agung Wiradewi
Format: Article
Language:English
Published: Sciendo 2024-01-01
Series:Forum of Clinical Oncology
Subjects:
Online Access:https://doi.org/10.2478/fco-2023-0010
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author Yudiana I Wayan
Marta Stacia Novia
Sugianto Ronald
Lestari Anak Agung Wiradewi
author_facet Yudiana I Wayan
Marta Stacia Novia
Sugianto Ronald
Lestari Anak Agung Wiradewi
author_sort Yudiana I Wayan
collection DOAJ
description The spread of penile cancer cells through lymphatic vessels provides the potential for using compounds involved in lymphangiogenesis, such as programmed death-ligand 1 (PD-L1), C-reactive protein (CRP), neutrophil/lymphocyte ratio (NLR), and Ki-67, in predicting the development of lymphatic metastases in penile cancer.
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spelling doaj-art-38a503fa6a6f4d5abfe367a3ff7691fc2025-08-20T02:33:31ZengSciendoForum of Clinical Oncology1792-362X2024-01-01142253410.2478/fco-2023-0010Programmed Death-Ligand 1, C-reactive Protein, and Neutrophil/Lymphocyte Ratio as Lymphangiogenesis Markers of Metastasis in Penile Cancer – A Systematic ReviewYudiana I Wayan0Marta Stacia Novia1Sugianto Ronald2Lestari Anak Agung Wiradewi3Department of Urology, Faculty of Medicine, Universitas Udayana, Prof. Dr. I.G.N.G Ngoerah General Hospital, Bali, IndonesiaDepartment of Surgery, Faculty of Medicine, Universitas Udayana, Prof. Dr. I.G.N.G Ngoerah General Hospital, Bali, IndonesiaDepartment of Urology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General-Academic Hospital, Surabaya, East Java, IndonesiaDepartment of Clinical Pathology, Faculty of Medicine, Universitas Udayana, Prof. Dr. I.G.N.G Ngoerah General Hospital, Bali, IndonesiaThe spread of penile cancer cells through lymphatic vessels provides the potential for using compounds involved in lymphangiogenesis, such as programmed death-ligand 1 (PD-L1), C-reactive protein (CRP), neutrophil/lymphocyte ratio (NLR), and Ki-67, in predicting the development of lymphatic metastases in penile cancer.https://doi.org/10.2478/fco-2023-0010biomarkerslymphatic metastasispenile cancerprogrammed death-ligand 1c-reactive proteinneutrophil/lymphocyte ratio
spellingShingle Yudiana I Wayan
Marta Stacia Novia
Sugianto Ronald
Lestari Anak Agung Wiradewi
Programmed Death-Ligand 1, C-reactive Protein, and Neutrophil/Lymphocyte Ratio as Lymphangiogenesis Markers of Metastasis in Penile Cancer – A Systematic Review
Forum of Clinical Oncology
biomarkers
lymphatic metastasis
penile cancer
programmed death-ligand 1
c-reactive protein
neutrophil/lymphocyte ratio
title Programmed Death-Ligand 1, C-reactive Protein, and Neutrophil/Lymphocyte Ratio as Lymphangiogenesis Markers of Metastasis in Penile Cancer – A Systematic Review
title_full Programmed Death-Ligand 1, C-reactive Protein, and Neutrophil/Lymphocyte Ratio as Lymphangiogenesis Markers of Metastasis in Penile Cancer – A Systematic Review
title_fullStr Programmed Death-Ligand 1, C-reactive Protein, and Neutrophil/Lymphocyte Ratio as Lymphangiogenesis Markers of Metastasis in Penile Cancer – A Systematic Review
title_full_unstemmed Programmed Death-Ligand 1, C-reactive Protein, and Neutrophil/Lymphocyte Ratio as Lymphangiogenesis Markers of Metastasis in Penile Cancer – A Systematic Review
title_short Programmed Death-Ligand 1, C-reactive Protein, and Neutrophil/Lymphocyte Ratio as Lymphangiogenesis Markers of Metastasis in Penile Cancer – A Systematic Review
title_sort programmed death ligand 1 c reactive protein and neutrophil lymphocyte ratio as lymphangiogenesis markers of metastasis in penile cancer a systematic review
topic biomarkers
lymphatic metastasis
penile cancer
programmed death-ligand 1
c-reactive protein
neutrophil/lymphocyte ratio
url https://doi.org/10.2478/fco-2023-0010
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