Epigenetic dynamics of partially methylated domains in human placenta and trophoblast stem cells

Epigenetic dynamics of partially methylated domains in human placenta and trophoblast stem cells

Abstract Background The placenta is essential for nutrient exchange and hormone production between the mother and the developing fetus and serves as an invaluable model for epigenetic research. Most epigenetic studies of the human placenta have used whole placentas from term pregnancies and have ide...

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Main Authors: Hidehiro Toh, Hiroaki Okae, Kenjiro Shirane, Tetsuya Sato, Hirotaka Hamada, Chie Kikutake, Daisuke Saito, Takahiro Arima, Hiroyuki Sasaki, Mikita Suyama
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Genomics
Subjects:
Human cytotrophoblasts
Human trophoblast stem cells
Partially methylated domains
Methylomes
Online Access:https://doi.org/10.1186/s12864-024-10986-9
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