TCF12 enhances angiogenesis and affects sorafenib response in liver cancer via HIF-1α interaction

TCF12 enhances angiogenesis and affects sorafenib response in liver cancer via HIF-1α interaction

Transcription factor 12 (TCF12), a member of the basic Helix-Loop-Helix (bHLH) protein family, plays a crucial role in regulating cell growth and differentiation. It has been implicated in the development and progression of malignant tumors; however, its specific mechanisms in vascularization and d...

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Bibliographic Details
Main Authors: Yuanbin Chen, Xiaolong Wang, Jin Chen, Min Dai, Xinyue Zhang, Jie Yin, Xiao He
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2025-04-01
Series:Biomolecules & Biomedicine
Subjects:
Transcription factor 12
TCF12
Hypoxia-Inducible Factor 1-alpha
HIF-1α
angiogenesis
sorafenib
Online Access:http://www.bjbms.org/ojs/index.php/bjbms/article/view/12022
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