Home High-Flow Nasal Cannula in Patients with Chronic Respiratory Failure: A Literature Review and Suggestions for Clinical Practice
High-flow nasal cannula (HFNC) is a noninvasive respiratory support system that delivers air that is heated at 31°C−38°C, humidified 100%, and oxygen-enriched at a constant high flow rate of 15−60 L/min. Because of its numerous physiological benefits, convenience, and minimal side effects, HFNC has...
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The Korean Academy of Tuberculosis and Respiratory Diseases
2025-04-01
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| Series: | Tuberculosis and Respiratory Diseases |
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| Online Access: | http://e-trd.org/upload/pdf/trd-2024-0196.pdf |
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| author | Youjin Chang Moon Seong Baek Sei Won Kim Su Hwan Lee Jung Soo Kim So Young Park Jin Woo Kim Jae Hwa Cho Sunghoon Park |
| author_facet | Youjin Chang Moon Seong Baek Sei Won Kim Su Hwan Lee Jung Soo Kim So Young Park Jin Woo Kim Jae Hwa Cho Sunghoon Park |
| author_sort | Youjin Chang |
| collection | DOAJ |
| description | High-flow nasal cannula (HFNC) is a noninvasive respiratory support system that delivers air that is heated at 31°C−38°C, humidified 100%, and oxygen-enriched at a constant high flow rate of 15−60 L/min. Because of its numerous physiological benefits, convenience, and minimal side effects, HFNC has been increasingly used over the past decade in patients with acute hypoxemic respiratory failure, yet the clinical benefits of long-term HFNC remain uncertain. Several studies have suggested its potential use as an alternative home oxygen therapy for patients with chronic stable lung diseases, such as chronic obstructive pulmonary disease (COPD), interstitial lung disease, and bronchiectasis. The use of long-term home HFNC in patients with chronic respiratory failure is an emerging area with promising potential. Despite limited clinical research, this review aims to describe the physiology of HFNC use and summarize the current evidence on its long-term application, to provide healthcare providers with insights and perspectives on the potential role of long-term home HFNC. |
| format | Article |
| id | doaj-art-38965323618a47fca6ecf2b00a3f913b |
| institution | OA Journals |
| issn | 1738-3536 2005-6184 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | The Korean Academy of Tuberculosis and Respiratory Diseases |
| record_format | Article |
| series | Tuberculosis and Respiratory Diseases |
| spelling | doaj-art-38965323618a47fca6ecf2b00a3f913b2025-08-20T02:08:12ZengThe Korean Academy of Tuberculosis and Respiratory DiseasesTuberculosis and Respiratory Diseases1738-35362005-61842025-04-0188226427710.4046/trd.2024.01964927Home High-Flow Nasal Cannula in Patients with Chronic Respiratory Failure: A Literature Review and Suggestions for Clinical PracticeYoujin Chang0Moon Seong Baek1Sei Won Kim2Su Hwan Lee3Jung Soo Kim4So Young Park5Jin Woo Kim6Jae Hwa Cho7Sunghoon Park8 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Republic of Korea Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea Department of Pulmonary, Critical Care and Sleep Medicine, Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inha University Hospital, Incheon, Republic of Korea Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangdong Sacred Heart Hospital, Seoul, Republic of Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Republic of Korea Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea Department of Pulmonary, Allergy and Critical Care Medicine, Hallym University Sacred Heart Hospital, Anyang, Republic of KoreaHigh-flow nasal cannula (HFNC) is a noninvasive respiratory support system that delivers air that is heated at 31°C−38°C, humidified 100%, and oxygen-enriched at a constant high flow rate of 15−60 L/min. Because of its numerous physiological benefits, convenience, and minimal side effects, HFNC has been increasingly used over the past decade in patients with acute hypoxemic respiratory failure, yet the clinical benefits of long-term HFNC remain uncertain. Several studies have suggested its potential use as an alternative home oxygen therapy for patients with chronic stable lung diseases, such as chronic obstructive pulmonary disease (COPD), interstitial lung disease, and bronchiectasis. The use of long-term home HFNC in patients with chronic respiratory failure is an emerging area with promising potential. Despite limited clinical research, this review aims to describe the physiology of HFNC use and summarize the current evidence on its long-term application, to provide healthcare providers with insights and perspectives on the potential role of long-term home HFNC.http://e-trd.org/upload/pdf/trd-2024-0196.pdfhigh-flow nasal cannulahomeoxygenchronic lung disease |
| spellingShingle | Youjin Chang Moon Seong Baek Sei Won Kim Su Hwan Lee Jung Soo Kim So Young Park Jin Woo Kim Jae Hwa Cho Sunghoon Park Home High-Flow Nasal Cannula in Patients with Chronic Respiratory Failure: A Literature Review and Suggestions for Clinical Practice Tuberculosis and Respiratory Diseases high-flow nasal cannula home oxygen chronic lung disease |
| title | Home High-Flow Nasal Cannula in Patients with Chronic Respiratory Failure: A Literature Review and Suggestions for Clinical Practice |
| title_full | Home High-Flow Nasal Cannula in Patients with Chronic Respiratory Failure: A Literature Review and Suggestions for Clinical Practice |
| title_fullStr | Home High-Flow Nasal Cannula in Patients with Chronic Respiratory Failure: A Literature Review and Suggestions for Clinical Practice |
| title_full_unstemmed | Home High-Flow Nasal Cannula in Patients with Chronic Respiratory Failure: A Literature Review and Suggestions for Clinical Practice |
| title_short | Home High-Flow Nasal Cannula in Patients with Chronic Respiratory Failure: A Literature Review and Suggestions for Clinical Practice |
| title_sort | home high flow nasal cannula in patients with chronic respiratory failure a literature review and suggestions for clinical practice |
| topic | high-flow nasal cannula home oxygen chronic lung disease |
| url | http://e-trd.org/upload/pdf/trd-2024-0196.pdf |
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