Circulating DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer

Circulating DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer

Abstract Plasma DNA methylation SEPTIN9, Syndecan 2 (SDC2), and Branched Chain Amino Acid Transaminase 1 (BCAT1) tests have served as valuable diagnostic, prognostic, and predictive markers for colorectal cancer (CRC). In this study, we analyzed data including 104 eligible CRC patients, 138 colorect...

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Main Authors: Beibei Chen, Huan Zhao, Huihui Hu, Haili Shang, Hui Wang, Zhentao Yao, Jinxi Huang, Huifang Lv, Weifeng Xu, Jianzheng Wang, Caiyun Nie, Jing Zhao, Yunduan He, Saiqi Wang, Xiaobing Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Circulating tumor DNA
DNA methylation
Colorectal cancer
Biomarker
Online Access:https://doi.org/10.1038/s41598-025-95712-5
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