Nasolabial Ulcerated Placard Revealing a Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma
Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma is a rare entity representing less than 1% of cutaneous lymphomas. It has an aggressive clinical manifestation with a poor prognosis. It is characterized by cytotoxic and epidermotropic CD8+ proliferation. It also expresses the TIA-1 m...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2022/5672783 |
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| author | J. B. Ntihebuwayo F. Hali A. Kerouach H. Rachadi S. Chiheb F. Marnissi |
| author_facet | J. B. Ntihebuwayo F. Hali A. Kerouach H. Rachadi S. Chiheb F. Marnissi |
| author_sort | J. B. Ntihebuwayo |
| collection | DOAJ |
| description | Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma is a rare entity representing less than 1% of cutaneous lymphomas. It has an aggressive clinical manifestation with a poor prognosis. It is characterized by cytotoxic and epidermotropic CD8+ proliferation. It also expresses the TIA-1 marker. We report a new case for its display and aggressive character, diagnostic difficulty, and good therapeutic response to chemotherapy. This is a 62-year-old female patient admitted to the hospital for a nasolabial ulcerated placard evolving for two years. Clinical examination revealed submandibular lymph nodes. The specimen analysis associated with anatomoclinical manifestation was concluded for a primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma. Tumor extent assessment did not show any secondary localization. The blood tests and serology were unremarkable. The patient had benefited from a CHOEP-type multidrug therapy protocol with complete healing of the lesion after three courses of chemotherapy. |
| format | Article |
| id | doaj-art-388dab6b54f746738696f9dfcf9c09bb |
| institution | OA Journals |
| issn | 2090-6471 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-388dab6b54f746738696f9dfcf9c09bb2025-08-20T02:38:58ZengWileyCase Reports in Dermatological Medicine2090-64712022-01-01202210.1155/2022/5672783Nasolabial Ulcerated Placard Revealing a Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell LymphomaJ. B. Ntihebuwayo0F. Hali1A. Kerouach2H. Rachadi3S. Chiheb4F. Marnissi5Dermatology and Venereology DepartmentDermatology and Venereology DepartmentDermatology and Venereology DepartmentDermatology and Venereology DepartmentDermatology and Venereology DepartmentLaboratory of Pathological AnatomyPrimary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma is a rare entity representing less than 1% of cutaneous lymphomas. It has an aggressive clinical manifestation with a poor prognosis. It is characterized by cytotoxic and epidermotropic CD8+ proliferation. It also expresses the TIA-1 marker. We report a new case for its display and aggressive character, diagnostic difficulty, and good therapeutic response to chemotherapy. This is a 62-year-old female patient admitted to the hospital for a nasolabial ulcerated placard evolving for two years. Clinical examination revealed submandibular lymph nodes. The specimen analysis associated with anatomoclinical manifestation was concluded for a primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma. Tumor extent assessment did not show any secondary localization. The blood tests and serology were unremarkable. The patient had benefited from a CHOEP-type multidrug therapy protocol with complete healing of the lesion after three courses of chemotherapy.http://dx.doi.org/10.1155/2022/5672783 |
| spellingShingle | J. B. Ntihebuwayo F. Hali A. Kerouach H. Rachadi S. Chiheb F. Marnissi Nasolabial Ulcerated Placard Revealing a Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma Case Reports in Dermatological Medicine |
| title | Nasolabial Ulcerated Placard Revealing a Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma |
| title_full | Nasolabial Ulcerated Placard Revealing a Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma |
| title_fullStr | Nasolabial Ulcerated Placard Revealing a Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma |
| title_full_unstemmed | Nasolabial Ulcerated Placard Revealing a Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma |
| title_short | Nasolabial Ulcerated Placard Revealing a Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma |
| title_sort | nasolabial ulcerated placard revealing a primary cutaneous aggressive epidermotropic cd8 t cell lymphoma |
| url | http://dx.doi.org/10.1155/2022/5672783 |
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