COX‐2 in lung cancer: Mechanisms, development, and targeted therapies

COX‐2 in lung cancer: Mechanisms, development, and targeted therapies

Abstract Lung cancer (LC) is the leading cause of cancer‐related death worldwide, with non‐small cell lung cancer (NSCLC) comprising 85% of all cases. COX‐2, an enzyme induced significantly under stress conditions, catalyzes the conversion of free arachidonic acid into prostaglandins. It exhibits hi...

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Bibliographic Details
Main Authors: Xueqi Liu, Junli Zhang, Wenwu Sun, Jianping Cao, Zhuang Ma
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Chronic Diseases and Translational Medicine
Subjects:
COX‐2
lung cancer
PGE2
targeted therapy
tumor development
Online Access:https://doi.org/10.1002/cdt3.120
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