Mullerian-Type Ciliated Cyst of the Thigh with PAX-8 and WT1 Positivity: A Case Report and Review of the Literature
Mullerian-type ciliated cysts are uncommon lesions usually found in the lower extremities and perineal region of young females. They have however been reported in males and in other anatomic sites. The cyst lining is typically positive for estrogen receptor (ER), progesterone receptor (PR), PAX-8, a...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/2487820 |
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| author | Corinthia Fabien-Dupuis Brian Cooper Jeffrey Upperman Shengmei Zhou Nick Shillingford |
| author_facet | Corinthia Fabien-Dupuis Brian Cooper Jeffrey Upperman Shengmei Zhou Nick Shillingford |
| author_sort | Corinthia Fabien-Dupuis |
| collection | DOAJ |
| description | Mullerian-type ciliated cysts are uncommon lesions usually found in the lower extremities and perineal region of young females. They have however been reported in males and in other anatomic sites. The cyst lining is typically positive for estrogen receptor (ER), progesterone receptor (PR), PAX-8, and WT1 immunohistochemical stains. This staining pattern has led to the notion that these cysts are of Müllerian origin. The vast majority of cases are located in the dermis where the preferred nomenclature is cutaneous ciliated cyst (CCC). We report a case of Müllerian-type ciliated cyst in the thigh of a 16-year-old girl. Unlike most of the cases reported in the English literature, this cyst was not centered in the dermis. Only a few other cases of Müllerian-type ciliated cysts with no cutaneous connection have been reported. We propose the term ectopic Müllerian cyst for this rare subset of lesions that are not skin based as is the current case. |
| format | Article |
| id | doaj-art-386a356cfd3e4ece887bed189f0cea09 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-386a356cfd3e4ece887bed189f0cea092025-08-20T03:55:11ZengWileyCase Reports in Medicine1687-96271687-96352016-01-01201610.1155/2016/24878202487820Mullerian-Type Ciliated Cyst of the Thigh with PAX-8 and WT1 Positivity: A Case Report and Review of the LiteratureCorinthia Fabien-Dupuis0Brian Cooper1Jeffrey Upperman2Shengmei Zhou3Nick Shillingford4Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, Los Angeles, CA, USADepartment of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, Los Angeles, CA, USAKeck School of Medicine of the University of Southern California, Los Angeles, CA, USADepartment of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, Los Angeles, CA, USADepartment of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, Los Angeles, CA, USAMullerian-type ciliated cysts are uncommon lesions usually found in the lower extremities and perineal region of young females. They have however been reported in males and in other anatomic sites. The cyst lining is typically positive for estrogen receptor (ER), progesterone receptor (PR), PAX-8, and WT1 immunohistochemical stains. This staining pattern has led to the notion that these cysts are of Müllerian origin. The vast majority of cases are located in the dermis where the preferred nomenclature is cutaneous ciliated cyst (CCC). We report a case of Müllerian-type ciliated cyst in the thigh of a 16-year-old girl. Unlike most of the cases reported in the English literature, this cyst was not centered in the dermis. Only a few other cases of Müllerian-type ciliated cysts with no cutaneous connection have been reported. We propose the term ectopic Müllerian cyst for this rare subset of lesions that are not skin based as is the current case.http://dx.doi.org/10.1155/2016/2487820 |
| spellingShingle | Corinthia Fabien-Dupuis Brian Cooper Jeffrey Upperman Shengmei Zhou Nick Shillingford Mullerian-Type Ciliated Cyst of the Thigh with PAX-8 and WT1 Positivity: A Case Report and Review of the Literature Case Reports in Medicine |
| title | Mullerian-Type Ciliated Cyst of the Thigh with PAX-8 and WT1 Positivity: A Case Report and Review of the Literature |
| title_full | Mullerian-Type Ciliated Cyst of the Thigh with PAX-8 and WT1 Positivity: A Case Report and Review of the Literature |
| title_fullStr | Mullerian-Type Ciliated Cyst of the Thigh with PAX-8 and WT1 Positivity: A Case Report and Review of the Literature |
| title_full_unstemmed | Mullerian-Type Ciliated Cyst of the Thigh with PAX-8 and WT1 Positivity: A Case Report and Review of the Literature |
| title_short | Mullerian-Type Ciliated Cyst of the Thigh with PAX-8 and WT1 Positivity: A Case Report and Review of the Literature |
| title_sort | mullerian type ciliated cyst of the thigh with pax 8 and wt1 positivity a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2016/2487820 |
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