Extramedullary Plasmacytoma Diagnosed in an HIV-Positive Patient by an Unusual Clinical Presentation
The aim of this paper is to describe a case report of EMP in an HIV-positive patient. A 44-year-old, dark-skinned HIV-infected woman was referred to the Oral Diseases Treatment Center with a swelling at palate and left gingival fornix in the maxilla. Biopsy was taken and the oral lesion was diagnose...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2016/6305173 |
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| author | Paulo de Camargo Moraes Luiz Alexandre Thomaz Victor Angelo Martins Montalli José Luiz Cintra Junqueira Camila Maria Beder Ribeiro Luciana Butini Oliveira |
| author_facet | Paulo de Camargo Moraes Luiz Alexandre Thomaz Victor Angelo Martins Montalli José Luiz Cintra Junqueira Camila Maria Beder Ribeiro Luciana Butini Oliveira |
| author_sort | Paulo de Camargo Moraes |
| collection | DOAJ |
| description | The aim of this paper is to describe a case report of EMP in an HIV-positive patient. A 44-year-old, dark-skinned HIV-infected woman was referred to the Oral Diseases Treatment Center with a swelling at palate and left gingival fornix in the maxilla. Biopsy was taken and the oral lesion was diagnosed as EMP with well-differentiated plasma cells and restriction of the lambda light-chain. Skeletal survey was performed and no radiograph alterations were observed, thus supporting the diagnosis of EMP. Patient was referred to treatment and after two months of chemo and radiotherapy, an expanding lesion was observed in L5/S1 patient’s vertebrae. Biopsy of the spinal lesion was consistent with lymphoma with plasmocitary differentiation, supporting the diagnosis of multiple myeloma (MM). Regarding the medical history, the final diagnostic was an oral extramedullary plasmacytoma with rapid progression into multiple myeloma. It is crucial to emphasize the relevance of HIV infection as a risk factor for both aggressive clinical behavior and unusual clinical presentation of extramedullary plasmacytoma cases. |
| format | Article |
| id | doaj-art-38679ed2487e486bac6c3eb8c33c0c93 |
| institution | OA Journals |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-38679ed2487e486bac6c3eb8c33c0c932025-08-20T02:38:58ZengWileyCase Reports in Dentistry2090-64472090-64552016-01-01201610.1155/2016/63051736305173Extramedullary Plasmacytoma Diagnosed in an HIV-Positive Patient by an Unusual Clinical PresentationPaulo de Camargo Moraes0Luiz Alexandre Thomaz1Victor Angelo Martins Montalli2José Luiz Cintra Junqueira3Camila Maria Beder Ribeiro4Luciana Butini Oliveira5Department of Oral Surgery, School of Dentistry, SLMandic, Campinas, SP, BrazilDepartment of Oral Radiology, School of Dentistry, SLMandic, Campinas, SP, BrazilDepartment of Oral Pathology, School of Dentistry, SLMandic, Campinas, SP, BrazilDepartment of Oral Radiology, School of Dentistry, SLMandic, Campinas, SP, BrazilDepartment of Oral Pathology and Stomatology, FOP-UNICAMP, Piracicaba, SP, BrazilDepartment of Oral Radiology, School of Dentistry, SLMandic, Campinas, SP, BrazilThe aim of this paper is to describe a case report of EMP in an HIV-positive patient. A 44-year-old, dark-skinned HIV-infected woman was referred to the Oral Diseases Treatment Center with a swelling at palate and left gingival fornix in the maxilla. Biopsy was taken and the oral lesion was diagnosed as EMP with well-differentiated plasma cells and restriction of the lambda light-chain. Skeletal survey was performed and no radiograph alterations were observed, thus supporting the diagnosis of EMP. Patient was referred to treatment and after two months of chemo and radiotherapy, an expanding lesion was observed in L5/S1 patient’s vertebrae. Biopsy of the spinal lesion was consistent with lymphoma with plasmocitary differentiation, supporting the diagnosis of multiple myeloma (MM). Regarding the medical history, the final diagnostic was an oral extramedullary plasmacytoma with rapid progression into multiple myeloma. It is crucial to emphasize the relevance of HIV infection as a risk factor for both aggressive clinical behavior and unusual clinical presentation of extramedullary plasmacytoma cases.http://dx.doi.org/10.1155/2016/6305173 |
| spellingShingle | Paulo de Camargo Moraes Luiz Alexandre Thomaz Victor Angelo Martins Montalli José Luiz Cintra Junqueira Camila Maria Beder Ribeiro Luciana Butini Oliveira Extramedullary Plasmacytoma Diagnosed in an HIV-Positive Patient by an Unusual Clinical Presentation Case Reports in Dentistry |
| title | Extramedullary Plasmacytoma Diagnosed in an HIV-Positive Patient by an Unusual Clinical Presentation |
| title_full | Extramedullary Plasmacytoma Diagnosed in an HIV-Positive Patient by an Unusual Clinical Presentation |
| title_fullStr | Extramedullary Plasmacytoma Diagnosed in an HIV-Positive Patient by an Unusual Clinical Presentation |
| title_full_unstemmed | Extramedullary Plasmacytoma Diagnosed in an HIV-Positive Patient by an Unusual Clinical Presentation |
| title_short | Extramedullary Plasmacytoma Diagnosed in an HIV-Positive Patient by an Unusual Clinical Presentation |
| title_sort | extramedullary plasmacytoma diagnosed in an hiv positive patient by an unusual clinical presentation |
| url | http://dx.doi.org/10.1155/2016/6305173 |
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