Management of Challenging Psoriasis Clinical Scenarios

Abstract Psoriasis, a chronic inflammatory skin condition, can have a significant impact on patients’ quality of life. Adoption of novel and emerging treatments has significantly improved psoriasis care in clinical practice, but challenges remain. The ‘Bridging the Gaps in Challenging Psoriasis’ mee...

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Main Authors: Linda Stein Gold, Andrew Alexis, Brad P. Glick, Mona Shahriari, Eingun James Song, Bruce Strober, Najat M. Watch, Melodie Young
Format: Article
Language:English
Published: Adis, Springer Healthcare 2025-04-01
Series:Dermatology and Therapy
Subjects:
Online Access:https://doi.org/10.1007/s13555-025-01393-3
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author Linda Stein Gold
Andrew Alexis
Brad P. Glick
Mona Shahriari
Eingun James Song
Bruce Strober
Najat M. Watch
Melodie Young
author_facet Linda Stein Gold
Andrew Alexis
Brad P. Glick
Mona Shahriari
Eingun James Song
Bruce Strober
Najat M. Watch
Melodie Young
author_sort Linda Stein Gold
collection DOAJ
description Abstract Psoriasis, a chronic inflammatory skin condition, can have a significant impact on patients’ quality of life. Adoption of novel and emerging treatments has significantly improved psoriasis care in clinical practice, but challenges remain. The ‘Bridging the Gaps in Challenging Psoriasis’ meeting was held in October 2024 to discuss relevant evidence, knowledge gaps, and best practices pertaining to challenging presentations of psoriasis. This report captures important insights and practice impacting guidance gathered from the panel discussion on five topics. The meeting commenced with an in-depth discussion on managing psoriasis in high-impact areas (e.g., scalp, intertriginous regions, nails, and the palms and soles) followed by a discussion on the importance of identifying and addressing common comorbidities associated with psoriasis. The panel explored key considerations and unique challenges when treating psoriasis in patients with darker skin tones (‘skin of color’) and highlighted the need for tailored therapeutic approaches. A comprehensive dialogue ensued on strategies for managing primary and secondary treatment failures. The session concluded with a concise discussion on the future of psoriasis treatments and pharmacologic therapies currently being developed to manage psoriasis. While discussing various challenging psoriasis scenarios, the dermatology experts emphasized the need to approach psoriasis as a systemic disease and advocated for comprehensive management that addresses both the skin and the broader health of the patient.
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spelling doaj-art-386609f4ce424a898be277dd2e70144a2025-08-20T03:08:40ZengAdis, Springer HealthcareDermatology and Therapy2193-82102190-91722025-04-011561555156710.1007/s13555-025-01393-3Management of Challenging Psoriasis Clinical ScenariosLinda Stein Gold0Andrew Alexis1Brad P. Glick2Mona Shahriari3Eingun James Song4Bruce Strober5Najat M. Watch6Melodie Young7Henry Ford HealthWeill Cornell MedicineLarkin Community HospitalYale University School of MedicineFrontier DermatologyYale University School of MedicineHenry Ford HealthMindful DermatologyAbstract Psoriasis, a chronic inflammatory skin condition, can have a significant impact on patients’ quality of life. Adoption of novel and emerging treatments has significantly improved psoriasis care in clinical practice, but challenges remain. The ‘Bridging the Gaps in Challenging Psoriasis’ meeting was held in October 2024 to discuss relevant evidence, knowledge gaps, and best practices pertaining to challenging presentations of psoriasis. This report captures important insights and practice impacting guidance gathered from the panel discussion on five topics. The meeting commenced with an in-depth discussion on managing psoriasis in high-impact areas (e.g., scalp, intertriginous regions, nails, and the palms and soles) followed by a discussion on the importance of identifying and addressing common comorbidities associated with psoriasis. The panel explored key considerations and unique challenges when treating psoriasis in patients with darker skin tones (‘skin of color’) and highlighted the need for tailored therapeutic approaches. A comprehensive dialogue ensued on strategies for managing primary and secondary treatment failures. The session concluded with a concise discussion on the future of psoriasis treatments and pharmacologic therapies currently being developed to manage psoriasis. While discussing various challenging psoriasis scenarios, the dermatology experts emphasized the need to approach psoriasis as a systemic disease and advocated for comprehensive management that addresses both the skin and the broader health of the patient.https://doi.org/10.1007/s13555-025-01393-3PsoriasisChallenging casesHigh-impact sitesInadequate response to biologicsComorbiditiesSkin of color
spellingShingle Linda Stein Gold
Andrew Alexis
Brad P. Glick
Mona Shahriari
Eingun James Song
Bruce Strober
Najat M. Watch
Melodie Young
Management of Challenging Psoriasis Clinical Scenarios
Dermatology and Therapy
Psoriasis
Challenging cases
High-impact sites
Inadequate response to biologics
Comorbidities
Skin of color
title Management of Challenging Psoriasis Clinical Scenarios
title_full Management of Challenging Psoriasis Clinical Scenarios
title_fullStr Management of Challenging Psoriasis Clinical Scenarios
title_full_unstemmed Management of Challenging Psoriasis Clinical Scenarios
title_short Management of Challenging Psoriasis Clinical Scenarios
title_sort management of challenging psoriasis clinical scenarios
topic Psoriasis
Challenging cases
High-impact sites
Inadequate response to biologics
Comorbidities
Skin of color
url https://doi.org/10.1007/s13555-025-01393-3
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