Integrated analysis of tyrosine-induced MiRNA and mRNA expression profiles in melanocytes reveals the regulatory role of miR-1560-3p in melanin deposition in Xichuan black-bone chickens

Integrated analysis of tyrosine-induced MiRNA and mRNA expression profiles in melanocytes reveals the regulatory role of miR-1560-3p in melanin deposition in Xichuan black-bone chickens

Abstract Background Tyrosine is a prerequisite for melanin biosynthesis and plays a crucial role in the growth and development of melanocytes, but the underlying mechanism is still unclear. In our previous research, we added 10− 9-10− 6 mol/L tyrosine to the melanocytes of black-bone chickens and fo...

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Main Authors: Zhiyuan Zhang, Pengwei Zhang, Fumin He, Yingdong Hou, Xiaowen Geng, Ruilong Xu, Ruiting Li, Yadong Tian, Wenting Li, Guirong Sun, Ruirui Jiang, Xiaojun Liu, Ruili Han, Guoxi Li, Xiangtao Kang, Donghua Li
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Genomics
Subjects:
Tyrosine
Transcriptomic analysis
miR-1560-3p-VIP
Melanin deposition
Online Access:https://doi.org/10.1186/s12864-025-11543-8
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