Association between abdominal obesity and nutritional supplement use among Iranian adults in the Shahedieh cohort study

Abstract The relationship between the use of supplements and the presence of abdominal obesity is a topic that is currently being debated. The purpose of the present study was to evaluate the existence of such an association. The current cross-sectional investigation included a population of 9878 in...

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Main Authors: Sina Nouri, Akram Ghadiri-Anari, Saeed Hosseini, Narjes Hazar
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-85136-6
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author Sina Nouri
Akram Ghadiri-Anari
Saeed Hosseini
Narjes Hazar
author_facet Sina Nouri
Akram Ghadiri-Anari
Saeed Hosseini
Narjes Hazar
author_sort Sina Nouri
collection DOAJ
description Abstract The relationship between the use of supplements and the presence of abdominal obesity is a topic that is currently being debated. The purpose of the present study was to evaluate the existence of such an association. The current cross-sectional investigation included a population of 9878 individuals who were the focus of the study’s initial phase in the Shahedieh cohort study, conducted in Yazd, Iran. Waist circumference was measured with the help of an inflexible tape measure. In addition, the data regarding the consumption of various supplements, including multivitamins, folic acid, ferric compounds, omega 3, calcium, vitamin D, zinc, and other supplements, were collected through interviews conducted by trained interviewers. Among the entire sample, 4785 individuals (50.6%) were found to have abdominal obesity, while 4093 individuals (43.3%) reported using at least one type of supplements. In the simple regression analysis, all of the supplements, except for multivitamins and zinc, were identified as adverse factors for abdominal obesity. However, in the multivariable regression analysis, only ferric compounds remained significant as a protective factor (OR = 0.73, 95%CI: 0.57‒0.94). The findings of this study suggest that dietary supplements, particularly ferric compounds, may have implications for managing abdominal obesity. These findings could inform public health strategies by incorporating ferric compound supplementation into dietary interventions aimed at reducing abdominal obesity prevalence. Furthermore, the potential clinical application of ferric compounds highlights the need for integrating nutritional approaches in obesity management programs. However, longitudinal studies are needed to establish causal relationships and confirm the long-term effectiveness and safety of such interventions.
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spelling doaj-art-385b108435b848348e5336d8f73550fa2025-08-20T02:35:39ZengNature PortfolioScientific Reports2045-23222025-01-0115111010.1038/s41598-025-85136-6Association between abdominal obesity and nutritional supplement use among Iranian adults in the Shahedieh cohort studySina Nouri0Akram Ghadiri-Anari1Saeed Hosseini2Narjes Hazar3School of Medicine, Shahid Sadoughi University of Medical SciencesDiabetes Research Center, Shahid Sadoughi University of Medical SciencesDepartment of Epidemiology, School of Public Health, Iran University of Medical SciencesDiabetes Research Center, Shahid Sadoughi University of Medical SciencesAbstract The relationship between the use of supplements and the presence of abdominal obesity is a topic that is currently being debated. The purpose of the present study was to evaluate the existence of such an association. The current cross-sectional investigation included a population of 9878 individuals who were the focus of the study’s initial phase in the Shahedieh cohort study, conducted in Yazd, Iran. Waist circumference was measured with the help of an inflexible tape measure. In addition, the data regarding the consumption of various supplements, including multivitamins, folic acid, ferric compounds, omega 3, calcium, vitamin D, zinc, and other supplements, were collected through interviews conducted by trained interviewers. Among the entire sample, 4785 individuals (50.6%) were found to have abdominal obesity, while 4093 individuals (43.3%) reported using at least one type of supplements. In the simple regression analysis, all of the supplements, except for multivitamins and zinc, were identified as adverse factors for abdominal obesity. However, in the multivariable regression analysis, only ferric compounds remained significant as a protective factor (OR = 0.73, 95%CI: 0.57‒0.94). The findings of this study suggest that dietary supplements, particularly ferric compounds, may have implications for managing abdominal obesity. These findings could inform public health strategies by incorporating ferric compound supplementation into dietary interventions aimed at reducing abdominal obesity prevalence. Furthermore, the potential clinical application of ferric compounds highlights the need for integrating nutritional approaches in obesity management programs. However, longitudinal studies are needed to establish causal relationships and confirm the long-term effectiveness and safety of such interventions.https://doi.org/10.1038/s41598-025-85136-6Obesity, AbdominalDietary supplementsIranFerric Compounds
spellingShingle Sina Nouri
Akram Ghadiri-Anari
Saeed Hosseini
Narjes Hazar
Association between abdominal obesity and nutritional supplement use among Iranian adults in the Shahedieh cohort study
Scientific Reports
Obesity, Abdominal
Dietary supplements
Iran
Ferric Compounds
title Association between abdominal obesity and nutritional supplement use among Iranian adults in the Shahedieh cohort study
title_full Association between abdominal obesity and nutritional supplement use among Iranian adults in the Shahedieh cohort study
title_fullStr Association between abdominal obesity and nutritional supplement use among Iranian adults in the Shahedieh cohort study
title_full_unstemmed Association between abdominal obesity and nutritional supplement use among Iranian adults in the Shahedieh cohort study
title_short Association between abdominal obesity and nutritional supplement use among Iranian adults in the Shahedieh cohort study
title_sort association between abdominal obesity and nutritional supplement use among iranian adults in the shahedieh cohort study
topic Obesity, Abdominal
Dietary supplements
Iran
Ferric Compounds
url https://doi.org/10.1038/s41598-025-85136-6
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AT saeedhosseini associationbetweenabdominalobesityandnutritionalsupplementuseamongiranianadultsintheshahediehcohortstudy
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