Experience with Inhaled Iloprost Used in the Surgical Treatment of Chronic Postthromboembolic Pulmonary Hypertension
The paper describes a case of inhaled iloprost use in a female patient with severe respiratory failure after pulmonary artery thromboendarterectomy, who was on venovenous extracorporeal membrane oxygenation. To reduce pulmonary hypertension and to prevent reperfusion syndrome, the patient received i...
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2013-04-01
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| Series: | Общая реаниматология |
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| Online Access: | https://www.reanimatology.com/rmt/article/view/146 |
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| author | V. V. Lomivorotov M. N. Deryagin S. M. Efremov V. A. Shmyrev I. A. Kornilov A. M. Chernyavsky |
| author_facet | V. V. Lomivorotov M. N. Deryagin S. M. Efremov V. A. Shmyrev I. A. Kornilov A. M. Chernyavsky |
| author_sort | V. V. Lomivorotov |
| collection | DOAJ |
| description | The paper describes a case of inhaled iloprost use in a female patient with severe respiratory failure after pulmonary artery thromboendarterectomy, who was on venovenous extracorporeal membrane oxygenation. To reduce pulmonary hypertension and to prevent reperfusion syndrome, the patient received inhaled iloprost in a dose of 5 ^g every 3 hours during surgery and in the first two days after surgery. On day 14 after surgery, extracorporeal membrane oxygenation was stopped as there were satisfactory respiratory and hemodynamic parameters. Four days later, the patient was weaned from mechanical ventilation. The length of stay in the intensive care unit was 24 days. The patient was discharged from hospital in a satisfactory condition. Thus, the perioperative use of iloprost could reduce pulmonary artery pressure by twice; however, reperfusion syndrome could not prevent significant respiratory failure. The data available in the literature on the use of ilo-prost in patients after pulmonary artery thromboendarterectomy are single and their results are ambiguous. There is a need for large-scale multicenter studies in this group of patients. Key words: chronic postthromboembolic pulmonary hypertension, pulmonary artery thromboendarterectomy, iloprost, extracorporeal membrane oxygenation. |
| format | Article |
| id | doaj-art-38353dbef0fd46f5b1936cf53ea6ee99 |
| institution | Kabale University |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2013-04-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-38353dbef0fd46f5b1936cf53ea6ee992025-08-20T03:59:40ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102013-04-019210.15360/1813-9779-2013-2-35146Experience with Inhaled Iloprost Used in the Surgical Treatment of Chronic Postthromboembolic Pulmonary HypertensionV. V. Lomivorotov0M. N. Deryagin1S. M. Efremov2V. A. Shmyrev3I. A. Kornilov4A. M. Chernyavsky5Academician E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, NovosibirskAcademician E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, NovosibirskAcademician E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, NovosibirskAcademician E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, NovosibirskAcademician E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, NovosibirskAcademician E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, NovosibirskThe paper describes a case of inhaled iloprost use in a female patient with severe respiratory failure after pulmonary artery thromboendarterectomy, who was on venovenous extracorporeal membrane oxygenation. To reduce pulmonary hypertension and to prevent reperfusion syndrome, the patient received inhaled iloprost in a dose of 5 ^g every 3 hours during surgery and in the first two days after surgery. On day 14 after surgery, extracorporeal membrane oxygenation was stopped as there were satisfactory respiratory and hemodynamic parameters. Four days later, the patient was weaned from mechanical ventilation. The length of stay in the intensive care unit was 24 days. The patient was discharged from hospital in a satisfactory condition. Thus, the perioperative use of iloprost could reduce pulmonary artery pressure by twice; however, reperfusion syndrome could not prevent significant respiratory failure. The data available in the literature on the use of ilo-prost in patients after pulmonary artery thromboendarterectomy are single and their results are ambiguous. There is a need for large-scale multicenter studies in this group of patients. Key words: chronic postthromboembolic pulmonary hypertension, pulmonary artery thromboendarterectomy, iloprost, extracorporeal membrane oxygenation.https://www.reanimatology.com/rmt/article/view/146chronic postthromboembolic pulmonary hyperten |
| spellingShingle | V. V. Lomivorotov M. N. Deryagin S. M. Efremov V. A. Shmyrev I. A. Kornilov A. M. Chernyavsky Experience with Inhaled Iloprost Used in the Surgical Treatment of Chronic Postthromboembolic Pulmonary Hypertension Общая реаниматология chronic postthromboembolic pulmonary hyperten |
| title | Experience with Inhaled Iloprost Used in the Surgical Treatment of Chronic Postthromboembolic Pulmonary Hypertension |
| title_full | Experience with Inhaled Iloprost Used in the Surgical Treatment of Chronic Postthromboembolic Pulmonary Hypertension |
| title_fullStr | Experience with Inhaled Iloprost Used in the Surgical Treatment of Chronic Postthromboembolic Pulmonary Hypertension |
| title_full_unstemmed | Experience with Inhaled Iloprost Used in the Surgical Treatment of Chronic Postthromboembolic Pulmonary Hypertension |
| title_short | Experience with Inhaled Iloprost Used in the Surgical Treatment of Chronic Postthromboembolic Pulmonary Hypertension |
| title_sort | experience with inhaled iloprost used in the surgical treatment of chronic postthromboembolic pulmonary hypertension |
| topic | chronic postthromboembolic pulmonary hyperten |
| url | https://www.reanimatology.com/rmt/article/view/146 |
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