Metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature
68Ga-DOTATATE positron emission tomography (PET) is a molecular imaging technology which has shown superiority over 111In-octreotide scanning for the detection and staging of neuroendocrine tumors. We report three patients with pancreatic masses that were ultimately diagnosed as clear cell renal cel...
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| Format: | Article |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2018-07-01
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| Series: | World Journal of Nuclear Medicine |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_38_17 |
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| author | David Nadebaum Sze Lee Mehrdad Nikfarjam Andrew Scott |
| author_facet | David Nadebaum Sze Lee Mehrdad Nikfarjam Andrew Scott |
| author_sort | David Nadebaum |
| collection | DOAJ |
| description | 68Ga-DOTATATE positron emission tomography (PET) is a molecular imaging technology which has shown superiority over 111In-octreotide scanning for the detection and staging of neuroendocrine tumors. We report three patients with pancreatic masses that were ultimately diagnosed as clear cell renal cell carcinoma (ccRCC) metastases on histopathology. During their initial diagnostic assessment, the three patients underwent both 18F-fluorodeoxyglucose (18F-FDG) and 68Ga-DOTATATE PET. While all three patients' lesions showed variable 18F-FDG avidity, uptake on 68Ga-DOTATATE PET was comparatively intense. The small case series illustrates the need to consider ccRCC in the differential diagnosis of 68Ga-DOTATATE avid lesions. |
| format | Article |
| id | doaj-art-3832c9f84f9248cd8be5f0acb9d48cb0 |
| institution | DOAJ |
| issn | 1450-1147 1607-3312 |
| language | English |
| publishDate | 2018-07-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | World Journal of Nuclear Medicine |
| spelling | doaj-art-3832c9f84f9248cd8be5f0acb9d48cb02025-08-20T02:54:43ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122018-07-01170319519710.4103/wjnm.WJNM_38_17Metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68Ga-DOTATATE positron emission tomography: Three case reports and a review of the literatureDavid Nadebaum0Sze Lee1Mehrdad Nikfarjam2Andrew Scott3Department of Molecular Imaging and Therapy, University of Melbourne, Austin Health, Melbourne, Victoria, AustraliaDepartment of Molecular Imaging and Therapy, University of Melbourne, Austin Health, Melbourne, Victoria, AustraliaDepartment of Surgery, Austin Health, University of Melbourne, Melbourne, Victoria, AustraliaDepartment of Molecular Imaging and Therapy, University of Melbourne, Austin Health, Melbourne, Victoria, Australia68Ga-DOTATATE positron emission tomography (PET) is a molecular imaging technology which has shown superiority over 111In-octreotide scanning for the detection and staging of neuroendocrine tumors. We report three patients with pancreatic masses that were ultimately diagnosed as clear cell renal cell carcinoma (ccRCC) metastases on histopathology. During their initial diagnostic assessment, the three patients underwent both 18F-fluorodeoxyglucose (18F-FDG) and 68Ga-DOTATATE PET. While all three patients' lesions showed variable 18F-FDG avidity, uptake on 68Ga-DOTATATE PET was comparatively intense. The small case series illustrates the need to consider ccRCC in the differential diagnosis of 68Ga-DOTATATE avid lesions.http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_38_17 68ga-dotatatekidney neoplasmspositron emission tomographyrenal cell carcinomasomatostatin receptors |
| spellingShingle | David Nadebaum Sze Lee Mehrdad Nikfarjam Andrew Scott Metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature World Journal of Nuclear Medicine 68ga-dotatate kidney neoplasms positron emission tomography renal cell carcinoma somatostatin receptors |
| title | Metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature |
| title_full | Metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature |
| title_fullStr | Metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature |
| title_full_unstemmed | Metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature |
| title_short | Metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature |
| title_sort | metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68ga dotatate positron emission tomography three case reports and a review of the literature |
| topic | 68ga-dotatate kidney neoplasms positron emission tomography renal cell carcinoma somatostatin receptors |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_38_17 |
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