Neuroanatomical and functional correlates in borderline personality disorder: A narrative review
Abstract Borderline personality disorder (BPD) is a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic. High suicidality in BPD patients underlines the significance of research into its patholog...
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| Language: | English |
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Wiley-VCH
2025-03-01
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| Series: | Ibrain |
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| Online Access: | https://doi.org/10.1002/ibra.12190 |
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| author | Giulio Perrotta |
| author_facet | Giulio Perrotta |
| author_sort | Giulio Perrotta |
| collection | DOAJ |
| description | Abstract Borderline personality disorder (BPD) is a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic. High suicidality in BPD patients underlines the significance of research into its pathology. While extensive research on the psychological and behavioral manifestations of BPD can be found in literature, the neuropsychological aspects of the disorder are still partially unknown, although the roles of certain brain structures in the manifestation of the pathology, such as the amygdala, hippocampus, insula, medial prefrontal and cingulate cortices, nucleus accumbens, and temporo‐occipital areas, have already been clarified. This review aims to synthesize current knowledge of the neuroanatomical and functional correlates of BPD, providing insights that may inform future research and therapeutic strategies. |
| format | Article |
| id | doaj-art-383147dff41f41829ce5ff001e478eee |
| institution | DOAJ |
| issn | 2313-1934 2769-2795 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Ibrain |
| spelling | doaj-art-383147dff41f41829ce5ff001e478eee2025-08-20T02:55:52ZengWiley-VCHIbrain2313-19342769-27952025-03-01111193110.1002/ibra.12190Neuroanatomical and functional correlates in borderline personality disorder: A narrative reviewGiulio Perrotta0Psychology and Psychotherapy Istituto per lo Studio delle Psicoterapie (I.S.P.) Rome Lazio ItalyAbstract Borderline personality disorder (BPD) is a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic. High suicidality in BPD patients underlines the significance of research into its pathology. While extensive research on the psychological and behavioral manifestations of BPD can be found in literature, the neuropsychological aspects of the disorder are still partially unknown, although the roles of certain brain structures in the manifestation of the pathology, such as the amygdala, hippocampus, insula, medial prefrontal and cingulate cortices, nucleus accumbens, and temporo‐occipital areas, have already been clarified. This review aims to synthesize current knowledge of the neuroanatomical and functional correlates of BPD, providing insights that may inform future research and therapeutic strategies.https://doi.org/10.1002/ibra.12190amygdalaborderlineborderline personality disorderlimbic systemprefrontal |
| spellingShingle | Giulio Perrotta Neuroanatomical and functional correlates in borderline personality disorder: A narrative review Ibrain amygdala borderline borderline personality disorder limbic system prefrontal |
| title | Neuroanatomical and functional correlates in borderline personality disorder: A narrative review |
| title_full | Neuroanatomical and functional correlates in borderline personality disorder: A narrative review |
| title_fullStr | Neuroanatomical and functional correlates in borderline personality disorder: A narrative review |
| title_full_unstemmed | Neuroanatomical and functional correlates in borderline personality disorder: A narrative review |
| title_short | Neuroanatomical and functional correlates in borderline personality disorder: A narrative review |
| title_sort | neuroanatomical and functional correlates in borderline personality disorder a narrative review |
| topic | amygdala borderline borderline personality disorder limbic system prefrontal |
| url | https://doi.org/10.1002/ibra.12190 |
| work_keys_str_mv | AT giulioperrotta neuroanatomicalandfunctionalcorrelatesinborderlinepersonalitydisorderanarrativereview |