Synthesis and Characterization of New Benzothiazole-derived Schiff Bases Metal Complexes

Nitrogen-comprising heterocyclic compounds and their derivatives have empirically been invaluable as therapeutic agents. Fundamentally, 4-chloro-6-nitro-2-amino-1,3-benzothiazole 1 was synthesized via bromination of 2-chloro-4-nitro aniline with ammonium thiocyanate. This new heterocyclic haloorgan...

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Main Authors: Wasan Abdul Razzaq Mahmood, Areej Kamal Assim Aldabbagh, Muhanned A. Mahmoud
Format: Article
Language:English
Published: University of Baghdad, College of Science for Women 2022-04-01
Series:مجلة بغداد للعلوم
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Online Access:https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/6059
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author Wasan Abdul Razzaq Mahmood
Areej Kamal Assim Aldabbagh
Muhanned A. Mahmoud
author_facet Wasan Abdul Razzaq Mahmood
Areej Kamal Assim Aldabbagh
Muhanned A. Mahmoud
author_sort Wasan Abdul Razzaq Mahmood
collection DOAJ
description Nitrogen-comprising heterocyclic compounds and their derivatives have empirically been invaluable as therapeutic agents. Fundamentally, 4-chloro-6-nitro-2-amino-1,3-benzothiazole 1 was synthesized via bromination of 2-chloro-4-nitro aniline with ammonium thiocyanate. This new heterocyclic haloorganoamino-1,3-benzothiazole derivative, was a starting material, which condensed and tethered with three different aromatic aldehyde pendant arm in presence of ethanol and glacial acetic acid isolating an interesting sequence of tridentate Schiff bases 2-4. These compounds were used for complexation reactions in 1:1 (metal: ligand) stoichiometry to obtain heteroleptic Al(III), Ni (II) and K(I) benzothiazole chelates 5-7(a-c) of the type [Al(L)Cl2, Ni(L)Cl, K(L) {L = Schiff base derivatives}]. The newly synthesized complexes were characterized by the melting points, IR and some of them by 1H-NMR spectroscopy and only one by X-ray techniques. The structures of complexes were anticipated from the spectroscopic studies.
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series مجلة بغداد للعلوم
spelling doaj-art-382b5f0b45ca4bb6a5ba52cf1d8c08062025-08-20T03:56:13ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862022-04-0119210.21123/bsj.2022.19.2.0378Synthesis and Characterization of New Benzothiazole-derived Schiff Bases Metal ComplexesWasan Abdul Razzaq Mahmood0Areej Kamal Assim Aldabbagh1Muhanned A. Mahmoud2Department of Chemistry/ College of Science for Woman, University of Baghdad, Baghdad, IraqDepartment of Chemistry/ College of Science for Woman, University of Baghdad, Baghdad, IraqDepartment of Physiology, Biochemistry and Pharmacology/ College of Veterinary Medicine, University of Baghdad, Baghdad, Iraq Nitrogen-comprising heterocyclic compounds and their derivatives have empirically been invaluable as therapeutic agents. Fundamentally, 4-chloro-6-nitro-2-amino-1,3-benzothiazole 1 was synthesized via bromination of 2-chloro-4-nitro aniline with ammonium thiocyanate. This new heterocyclic haloorganoamino-1,3-benzothiazole derivative, was a starting material, which condensed and tethered with three different aromatic aldehyde pendant arm in presence of ethanol and glacial acetic acid isolating an interesting sequence of tridentate Schiff bases 2-4. These compounds were used for complexation reactions in 1:1 (metal: ligand) stoichiometry to obtain heteroleptic Al(III), Ni (II) and K(I) benzothiazole chelates 5-7(a-c) of the type [Al(L)Cl2, Ni(L)Cl, K(L) {L = Schiff base derivatives}]. The newly synthesized complexes were characterized by the melting points, IR and some of them by 1H-NMR spectroscopy and only one by X-ray techniques. The structures of complexes were anticipated from the spectroscopic studies. https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/6059aniline, 1,3-benzothiazole, ligand, metal complexes, Schiff bases
spellingShingle Wasan Abdul Razzaq Mahmood
Areej Kamal Assim Aldabbagh
Muhanned A. Mahmoud
Synthesis and Characterization of New Benzothiazole-derived Schiff Bases Metal Complexes
مجلة بغداد للعلوم
aniline, 1,3-benzothiazole, ligand, metal complexes, Schiff bases
title Synthesis and Characterization of New Benzothiazole-derived Schiff Bases Metal Complexes
title_full Synthesis and Characterization of New Benzothiazole-derived Schiff Bases Metal Complexes
title_fullStr Synthesis and Characterization of New Benzothiazole-derived Schiff Bases Metal Complexes
title_full_unstemmed Synthesis and Characterization of New Benzothiazole-derived Schiff Bases Metal Complexes
title_short Synthesis and Characterization of New Benzothiazole-derived Schiff Bases Metal Complexes
title_sort synthesis and characterization of new benzothiazole derived schiff bases metal complexes
topic aniline, 1,3-benzothiazole, ligand, metal complexes, Schiff bases
url https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/6059
work_keys_str_mv AT wasanabdulrazzaqmahmood synthesisandcharacterizationofnewbenzothiazolederivedschiffbasesmetalcomplexes
AT areejkamalassimaldabbagh synthesisandcharacterizationofnewbenzothiazolederivedschiffbasesmetalcomplexes
AT muhannedamahmoud synthesisandcharacterizationofnewbenzothiazolederivedschiffbasesmetalcomplexes