Increased Expression of the Calcium-Activated Chloride Channel in Hclca1 in Airways of Patients with Obstructive Chronic Bronchitis
BACKGROUND: Interleukin (IL)-9 and its effect on enhancing the human calcium-activated chloride channel 1 (hCLCA1) expression have been shown to induce mucin production. Increased expression of hCLCA1 may, in turn, contribute to mucus overproduction in chronic obstructive pulmonary disease (COPD) wi...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2005-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2005/531432 |
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| _version_ | 1849693153438728192 |
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| author | Hans-Peter Hauber Celine Bergeron Anne Tsicopoulos Benoit Wallaert Ron Olivenstein Kenneth J Holroyd Roy C Levitt Qutayba Hamid |
| author_facet | Hans-Peter Hauber Celine Bergeron Anne Tsicopoulos Benoit Wallaert Ron Olivenstein Kenneth J Holroyd Roy C Levitt Qutayba Hamid |
| author_sort | Hans-Peter Hauber |
| collection | DOAJ |
| description | BACKGROUND: Interleukin (IL)-9 and its effect on enhancing the human calcium-activated chloride channel 1 (hCLCA1) expression have been shown to induce mucin production. Increased expression of hCLCA1 may, in turn, contribute to mucus overproduction in chronic obstructive pulmonary disease (COPD) with a chronic bronchitis (CB) phenotype. |
| format | Article |
| id | doaj-art-381e3bf5688d4015852ce9ecb5d1fbdf |
| institution | DOAJ |
| issn | 1198-2241 |
| language | English |
| publishDate | 2005-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-381e3bf5688d4015852ce9ecb5d1fbdf2025-08-20T03:20:30ZengWileyCanadian Respiratory Journal1198-22412005-01-0112314314610.1155/2005/531432Increased Expression of the Calcium-Activated Chloride Channel in Hclca1 in Airways of Patients with Obstructive Chronic BronchitisHans-Peter Hauber0Celine Bergeron1Anne Tsicopoulos2Benoit Wallaert3Ron Olivenstein4Kenneth J Holroyd5Roy C Levitt6Qutayba Hamid7Meakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaMeakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaInstitut Pasteur, Lille, FranceInstitut Pasteur, Lille, FranceMeakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaGenaera Corporation, Plymouth Meeting, Pennsylvania, USAGenaera Corporation, Plymouth Meeting, Pennsylvania, USAMeakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaBACKGROUND: Interleukin (IL)-9 and its effect on enhancing the human calcium-activated chloride channel 1 (hCLCA1) expression have been shown to induce mucin production. Increased expression of hCLCA1 may, in turn, contribute to mucus overproduction in chronic obstructive pulmonary disease (COPD) with a chronic bronchitis (CB) phenotype.http://dx.doi.org/10.1155/2005/531432 |
| spellingShingle | Hans-Peter Hauber Celine Bergeron Anne Tsicopoulos Benoit Wallaert Ron Olivenstein Kenneth J Holroyd Roy C Levitt Qutayba Hamid Increased Expression of the Calcium-Activated Chloride Channel in Hclca1 in Airways of Patients with Obstructive Chronic Bronchitis Canadian Respiratory Journal |
| title | Increased Expression of the Calcium-Activated Chloride Channel in Hclca1 in Airways of Patients with Obstructive Chronic Bronchitis |
| title_full | Increased Expression of the Calcium-Activated Chloride Channel in Hclca1 in Airways of Patients with Obstructive Chronic Bronchitis |
| title_fullStr | Increased Expression of the Calcium-Activated Chloride Channel in Hclca1 in Airways of Patients with Obstructive Chronic Bronchitis |
| title_full_unstemmed | Increased Expression of the Calcium-Activated Chloride Channel in Hclca1 in Airways of Patients with Obstructive Chronic Bronchitis |
| title_short | Increased Expression of the Calcium-Activated Chloride Channel in Hclca1 in Airways of Patients with Obstructive Chronic Bronchitis |
| title_sort | increased expression of the calcium activated chloride channel in hclca1 in airways of patients with obstructive chronic bronchitis |
| url | http://dx.doi.org/10.1155/2005/531432 |
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