Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods
Summary: Dry conditions increase blood feeding in mosquitoes, but it is unknown if dehydration-induced bloodmeals are increased beyond what is necessary for reproduction. In this study, we investigated the role of dehydration in secondary blood feeding behaviors of mosquitoes. Following an initial b...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | iScience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004225000197 |
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| author | Christopher J. Holmes Souvik Chakraborty Oluwaseun M. Ajayi Melissa R. Uhran Ronja Frigard Crystal L. Stacey Emily E. Susanto Shyh-Chi Chen Jason L. Rasgon Matthew DeGennaro Yanyu Xiao Joshua B. Benoit |
| author_facet | Christopher J. Holmes Souvik Chakraborty Oluwaseun M. Ajayi Melissa R. Uhran Ronja Frigard Crystal L. Stacey Emily E. Susanto Shyh-Chi Chen Jason L. Rasgon Matthew DeGennaro Yanyu Xiao Joshua B. Benoit |
| author_sort | Christopher J. Holmes |
| collection | DOAJ |
| description | Summary: Dry conditions increase blood feeding in mosquitoes, but it is unknown if dehydration-induced bloodmeals are increased beyond what is necessary for reproduction. In this study, we investigated the role of dehydration in secondary blood feeding behaviors of mosquitoes. Following an initial bloodmeal, prolonged exposure to dry conditions increased secondary blood feeding in mosquitoes by nearly two-fold, and chronic blood feeding allowed mosquitoes to survive up to 20 days without access to water. Exposure to desiccating conditions following a bloodmeal resulted in increased activity, decreased sleep levels, and prompted a return of CO2 sensing before egg deposition. Increased blood feeding and higher survival during dry periods are predicted to increase pathogen transmission, allowing for a rapid rebound in mosquito populations when favorable conditions return. Overall, these results solidify our understanding of how dry periods impact mosquito blood feeding and the role that mosquito dehydration contributes to pathogen transmission dynamics. |
| format | Article |
| id | doaj-art-38017b37af504c0593aa5bba1c39a00f |
| institution | Kabale University |
| issn | 2589-0042 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj-art-38017b37af504c0593aa5bba1c39a00f2025-01-29T05:01:37ZengElsevieriScience2589-00422025-02-01282111760Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periodsChristopher J. Holmes0Souvik Chakraborty1Oluwaseun M. Ajayi2Melissa R. Uhran3Ronja Frigard4Crystal L. Stacey5Emily E. Susanto6Shyh-Chi Chen7Jason L. Rasgon8Matthew DeGennaro9Yanyu Xiao10Joshua B. Benoit11Department of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA; Corresponding authorDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USADepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USADepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USADepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USADepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USADepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USADepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USADepartment of Entomology, Center for Infectious Disease Dynamics and Huck Institutes for Life Sciences, Pennsylvania State University, University Park, PA 16802, USADepartment of Biological Sciences and Biomolecular Sciences Institute, Florida International University, Miami, FL 33199, USADepartment of Mathematical Sciences, University of Cincinnati, Cincinnati, OH 45221, USADepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA; Corresponding authorSummary: Dry conditions increase blood feeding in mosquitoes, but it is unknown if dehydration-induced bloodmeals are increased beyond what is necessary for reproduction. In this study, we investigated the role of dehydration in secondary blood feeding behaviors of mosquitoes. Following an initial bloodmeal, prolonged exposure to dry conditions increased secondary blood feeding in mosquitoes by nearly two-fold, and chronic blood feeding allowed mosquitoes to survive up to 20 days without access to water. Exposure to desiccating conditions following a bloodmeal resulted in increased activity, decreased sleep levels, and prompted a return of CO2 sensing before egg deposition. Increased blood feeding and higher survival during dry periods are predicted to increase pathogen transmission, allowing for a rapid rebound in mosquito populations when favorable conditions return. Overall, these results solidify our understanding of how dry periods impact mosquito blood feeding and the role that mosquito dehydration contributes to pathogen transmission dynamics.http://www.sciencedirect.com/science/article/pii/S2589004225000197VirologyEnvironmental healthEntomology |
| spellingShingle | Christopher J. Holmes Souvik Chakraborty Oluwaseun M. Ajayi Melissa R. Uhran Ronja Frigard Crystal L. Stacey Emily E. Susanto Shyh-Chi Chen Jason L. Rasgon Matthew DeGennaro Yanyu Xiao Joshua B. Benoit Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods iScience Virology Environmental health Entomology |
| title | Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods |
| title_full | Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods |
| title_fullStr | Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods |
| title_full_unstemmed | Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods |
| title_short | Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods |
| title_sort | multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods |
| topic | Virology Environmental health Entomology |
| url | http://www.sciencedirect.com/science/article/pii/S2589004225000197 |
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