Identification of compounds to promote diabetic wound healing based on transcriptome signature

Identification of compounds to promote diabetic wound healing based on transcriptome signature

PurposeDiabetic wounds are characterized by delayed healing, and the resulting diabetic foot ulcer may lead to severe complications, including amputations and mortality. This study aimed to identify potential small molecule drug candidates that can enhance diabetic wound healing through integrating...

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Main Authors: Jiamin Shang, Zhaoyu Liu, Meidai Liang, Zijie Yin, Zeyu Yang, Xiaomeng Ye, Guanhua Du, Xiuying Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
diabetic wound
bioinformatics
transcriptome
drug discovery
mechanism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1576056/full
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