Intramedullary Spinal Cord Metastasis in Spinal Ependymomas
Drop metastasis, or intramedullary spinal cord metastasis(ISCM), is a rare condition accounting 0.9%–5% of CNS orspinal metastases. It arises from tumour cell disseminationthrough cerebrospinal fluid (CSF), often affecting thethoracic and lumbar spine. Clinical features include rapidlyprogressive n...
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| Format: | Article |
| Language: | English |
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Pakistan Medical Association
2025-02-01
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| Series: | Journal of the Pakistan Medical Association |
| Online Access: | https://jpma.org.pk/index.php/public_html/article/view/30476 |
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| _version_ | 1850095442522537984 |
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| author | Zanib Javed Raheema Sadiq Hania Fatima Muhammad Shahzad Shamim |
| author_facet | Zanib Javed Raheema Sadiq Hania Fatima Muhammad Shahzad Shamim |
| author_sort | Zanib Javed |
| collection | DOAJ |
| description |
Drop metastasis, or intramedullary spinal cord metastasis(ISCM), is a rare condition accounting 0.9%–5% of CNS orspinal metastases. It arises from tumour cell disseminationthrough cerebrospinal fluid (CSF), often affecting thethoracic and lumbar spine. Clinical features include rapidlyprogressive neurological deficits, limb weakness, sensoryloss, and pain. Diagnosing drop metastasis is challengingand MRI with gadolinium remains the gold standardmodality for investigation. Surgical resection followed byradiotherapy remains the primary treatment option,whereas chemotherapy serves a palliative role in cases ofrecurrence or disseminated metastases.
Keywords: Ependymomas, Drop metastases, Radiotherapy
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| format | Article |
| id | doaj-art-37f7450dda564b97bf2ae6f5210bcb57 |
| institution | DOAJ |
| issn | 0030-9982 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Pakistan Medical Association |
| record_format | Article |
| series | Journal of the Pakistan Medical Association |
| spelling | doaj-art-37f7450dda564b97bf2ae6f5210bcb572025-08-20T02:41:26ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822025-02-01750310.47391/JPMA.25-22Intramedullary Spinal Cord Metastasis in Spinal EpendymomasZanib Javed0Raheema Sadiq1Hania Fatima2Muhammad Shahzad Shamim3Department of Surgery, Aga Khan University Hospital, Karachi PakistanDepartment of Surgery, Aga Khan University Hospital, Karachi PakistanDepartment of Surgery, Aga Khan University Hospital, Karachi PakistanDepartment of Surgery, Aga Khan University Hospital, Karachi Pakistan Drop metastasis, or intramedullary spinal cord metastasis(ISCM), is a rare condition accounting 0.9%–5% of CNS orspinal metastases. It arises from tumour cell disseminationthrough cerebrospinal fluid (CSF), often affecting thethoracic and lumbar spine. Clinical features include rapidlyprogressive neurological deficits, limb weakness, sensoryloss, and pain. Diagnosing drop metastasis is challengingand MRI with gadolinium remains the gold standardmodality for investigation. Surgical resection followed byradiotherapy remains the primary treatment option,whereas chemotherapy serves a palliative role in cases ofrecurrence or disseminated metastases. Keywords: Ependymomas, Drop metastases, Radiotherapy https://jpma.org.pk/index.php/public_html/article/view/30476 |
| spellingShingle | Zanib Javed Raheema Sadiq Hania Fatima Muhammad Shahzad Shamim Intramedullary Spinal Cord Metastasis in Spinal Ependymomas Journal of the Pakistan Medical Association |
| title | Intramedullary Spinal Cord Metastasis in Spinal Ependymomas |
| title_full | Intramedullary Spinal Cord Metastasis in Spinal Ependymomas |
| title_fullStr | Intramedullary Spinal Cord Metastasis in Spinal Ependymomas |
| title_full_unstemmed | Intramedullary Spinal Cord Metastasis in Spinal Ependymomas |
| title_short | Intramedullary Spinal Cord Metastasis in Spinal Ependymomas |
| title_sort | intramedullary spinal cord metastasis in spinal ependymomas |
| url | https://jpma.org.pk/index.php/public_html/article/view/30476 |
| work_keys_str_mv | AT zanibjaved intramedullaryspinalcordmetastasisinspinalependymomas AT raheemasadiq intramedullaryspinalcordmetastasisinspinalependymomas AT haniafatima intramedullaryspinalcordmetastasisinspinalependymomas AT muhammadshahzadshamim intramedullaryspinalcordmetastasisinspinalependymomas |