A triple-targeting “nano-brake” remodeling the impaired immune microenvironment in skin lesions for psoriasis treatment

A triple-targeting “nano-brake” remodeling the impaired immune microenvironment in skin lesions for psoriasis treatment

Psoriasis, a prevalent immune-mediated chronic inflammatory skin ailment, has been linked to heightened oxidative stress and compromised immune tolerance. Immune checkpoint pathways, particularly the programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) signaling axis, are instrument...

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Bibliographic Details
Main Authors: Ruijie Chen, Baiqun Duan, Shize Li, Yixuan Zhu, Zihao Huang, Dingchao Shen, Zhanzheng Ye, Yuqi Yan, Chenyu Qiu, Haoxiong Guan, Yinsha Yao, Jie Dong, Fugen Wu, Xinyu Jiang, Xianbao Shi, Longfa Kou
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
Subjects:
Psoriasis
Bilirubin
ROS
PD-1/PDL-1
Th17/Treg
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425004351
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