Beneficial Role of Mg2+ in Prevention and Treatment of Hypertension
Hypertension constitutes one of the most widespread pathological conditions in developed and developing countries. Currently, more than 1 billion people worldwide are affected by the condition, either as frank hypertension or as prehypertension, raising the risk for major long-term complications and...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2018/9013721 |
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| author | Andrea M. P. Romani |
| author_facet | Andrea M. P. Romani |
| author_sort | Andrea M. P. Romani |
| collection | DOAJ |
| description | Hypertension constitutes one of the most widespread pathological conditions in developed and developing countries. Currently, more than 1 billion people worldwide are affected by the condition, either as frank hypertension or as prehypertension, raising the risk for major long-term complications and life-threatening pathologies. The costs in terms of health care services, medications for the treatment of hypertension and its complications, and associated loss in productivity represent a major economic burden for the various countries. The necessity of developing treatments that are economically more sustainable and with better compliance has been increasing alongside the incidence of the pathology. Along these lines, attention has been paid to the implementation of affordable but nutritious diets that deliver appropriate levels of macro- and micronutrients as integral part of the diets themselves or as supplements. In particular, experimental and clinical evidence suggests that an appropriate intake of dietary magnesium can be beneficial in controlling blood pressure. Additional advantages of a more diffuse therapeutic and/or preventive utilization of magnesium supplements are the virtual absence of side-effects and their affordable costs. The present review will attempt to frame our knowledge of how magnesium exerts its beneficial effects on blood pressure maintenance, which may lead to the development of more effective treatments of hypertension and its main complications. |
| format | Article |
| id | doaj-art-37ebb68bc47d43ca9f4d40210adca8d5 |
| institution | OA Journals |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-37ebb68bc47d43ca9f4d40210adca8d52025-08-20T02:07:59ZengWileyInternational Journal of Hypertension2090-03842090-03922018-01-01201810.1155/2018/90137219013721Beneficial Role of Mg2+ in Prevention and Treatment of HypertensionAndrea M. P. Romani0Case Western Reserve University, School of Medicine, Department Physiology and Biophysics, 10900 Euclid Avenue, Cleveland, OH 44106-4970, USAHypertension constitutes one of the most widespread pathological conditions in developed and developing countries. Currently, more than 1 billion people worldwide are affected by the condition, either as frank hypertension or as prehypertension, raising the risk for major long-term complications and life-threatening pathologies. The costs in terms of health care services, medications for the treatment of hypertension and its complications, and associated loss in productivity represent a major economic burden for the various countries. The necessity of developing treatments that are economically more sustainable and with better compliance has been increasing alongside the incidence of the pathology. Along these lines, attention has been paid to the implementation of affordable but nutritious diets that deliver appropriate levels of macro- and micronutrients as integral part of the diets themselves or as supplements. In particular, experimental and clinical evidence suggests that an appropriate intake of dietary magnesium can be beneficial in controlling blood pressure. Additional advantages of a more diffuse therapeutic and/or preventive utilization of magnesium supplements are the virtual absence of side-effects and their affordable costs. The present review will attempt to frame our knowledge of how magnesium exerts its beneficial effects on blood pressure maintenance, which may lead to the development of more effective treatments of hypertension and its main complications.http://dx.doi.org/10.1155/2018/9013721 |
| spellingShingle | Andrea M. P. Romani Beneficial Role of Mg2+ in Prevention and Treatment of Hypertension International Journal of Hypertension |
| title | Beneficial Role of Mg2+ in Prevention and Treatment of Hypertension |
| title_full | Beneficial Role of Mg2+ in Prevention and Treatment of Hypertension |
| title_fullStr | Beneficial Role of Mg2+ in Prevention and Treatment of Hypertension |
| title_full_unstemmed | Beneficial Role of Mg2+ in Prevention and Treatment of Hypertension |
| title_short | Beneficial Role of Mg2+ in Prevention and Treatment of Hypertension |
| title_sort | beneficial role of mg2 in prevention and treatment of hypertension |
| url | http://dx.doi.org/10.1155/2018/9013721 |
| work_keys_str_mv | AT andreampromani beneficialroleofmg2inpreventionandtreatmentofhypertension |