A Novel Decentralized–Decoupled Fractional-Order Control Strategy for Complete Anesthesia–Hemodynamic Stabilization in Patients Undergoing Surgical Procedures

Within biomedical engineering, there has been significant collaboration among clinicians, control engineers, and researchers to tailor treatments to individual patients. Anesthesia is integral to numerous medical procedures, necessitating precise management of hypnosis, analgesia, neuromuscular bloc...

Full description

Saved in:
Bibliographic Details
Main Authors: Erwin T. Hegedüs, Isabela R. Birs, Clara M. Ionescu, Cristina I. Muresan
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Fractal and Fractional
Subjects:
Online Access:https://www.mdpi.com/2504-3110/8/11/623
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850267446387146752
author Erwin T. Hegedüs
Isabela R. Birs
Clara M. Ionescu
Cristina I. Muresan
author_facet Erwin T. Hegedüs
Isabela R. Birs
Clara M. Ionescu
Cristina I. Muresan
author_sort Erwin T. Hegedüs
collection DOAJ
description Within biomedical engineering, there has been significant collaboration among clinicians, control engineers, and researchers to tailor treatments to individual patients. Anesthesia is integral to numerous medical procedures, necessitating precise management of hypnosis, analgesia, neuromuscular blockade, and hemodynamic variables. Recent attention has focused on computer-controlled anesthesia and hemodynamic stabilization. This research proposes the integration of a decentralized control strategy for the induction phase with a decoupled control approach for the maintenance phase, aimed at mitigating interactions within the multivariable human system. The proposed strategy is based on fractional-order controllers. The solution is validated using an open-source patient simulator featuring data from 24 virtual patients, demonstrating the efficiency of the proposed approach with respect to decentralized control.
format Article
id doaj-art-37e8fd0ef1fa49cb8b395e1bd384246b
institution OA Journals
issn 2504-3110
language English
publishDate 2024-10-01
publisher MDPI AG
record_format Article
series Fractal and Fractional
spelling doaj-art-37e8fd0ef1fa49cb8b395e1bd384246b2025-08-20T01:53:48ZengMDPI AGFractal and Fractional2504-31102024-10-0181162310.3390/fractalfract8110623A Novel Decentralized–Decoupled Fractional-Order Control Strategy for Complete Anesthesia–Hemodynamic Stabilization in Patients Undergoing Surgical ProceduresErwin T. Hegedüs0Isabela R. Birs1Clara M. Ionescu2Cristina I. Muresan3Automation Department, Technical University of Cluj-Napoca, 400114 Cluj-Napoca, RomaniaAutomation Department, Technical University of Cluj-Napoca, 400114 Cluj-Napoca, RomaniaAutomation Department, Technical University of Cluj-Napoca, 400114 Cluj-Napoca, RomaniaAutomation Department, Technical University of Cluj-Napoca, 400114 Cluj-Napoca, RomaniaWithin biomedical engineering, there has been significant collaboration among clinicians, control engineers, and researchers to tailor treatments to individual patients. Anesthesia is integral to numerous medical procedures, necessitating precise management of hypnosis, analgesia, neuromuscular blockade, and hemodynamic variables. Recent attention has focused on computer-controlled anesthesia and hemodynamic stabilization. This research proposes the integration of a decentralized control strategy for the induction phase with a decoupled control approach for the maintenance phase, aimed at mitigating interactions within the multivariable human system. The proposed strategy is based on fractional-order controllers. The solution is validated using an open-source patient simulator featuring data from 24 virtual patients, demonstrating the efficiency of the proposed approach with respect to decentralized control.https://www.mdpi.com/2504-3110/8/11/623closed-loop control of anesthesiafractional-order controlmultivariable systemanesthesia controlhemodynamic controlinteraction
spellingShingle Erwin T. Hegedüs
Isabela R. Birs
Clara M. Ionescu
Cristina I. Muresan
A Novel Decentralized–Decoupled Fractional-Order Control Strategy for Complete Anesthesia–Hemodynamic Stabilization in Patients Undergoing Surgical Procedures
Fractal and Fractional
closed-loop control of anesthesia
fractional-order control
multivariable system
anesthesia control
hemodynamic control
interaction
title A Novel Decentralized–Decoupled Fractional-Order Control Strategy for Complete Anesthesia–Hemodynamic Stabilization in Patients Undergoing Surgical Procedures
title_full A Novel Decentralized–Decoupled Fractional-Order Control Strategy for Complete Anesthesia–Hemodynamic Stabilization in Patients Undergoing Surgical Procedures
title_fullStr A Novel Decentralized–Decoupled Fractional-Order Control Strategy for Complete Anesthesia–Hemodynamic Stabilization in Patients Undergoing Surgical Procedures
title_full_unstemmed A Novel Decentralized–Decoupled Fractional-Order Control Strategy for Complete Anesthesia–Hemodynamic Stabilization in Patients Undergoing Surgical Procedures
title_short A Novel Decentralized–Decoupled Fractional-Order Control Strategy for Complete Anesthesia–Hemodynamic Stabilization in Patients Undergoing Surgical Procedures
title_sort novel decentralized decoupled fractional order control strategy for complete anesthesia hemodynamic stabilization in patients undergoing surgical procedures
topic closed-loop control of anesthesia
fractional-order control
multivariable system
anesthesia control
hemodynamic control
interaction
url https://www.mdpi.com/2504-3110/8/11/623
work_keys_str_mv AT erwinthegedus anoveldecentralizeddecoupledfractionalordercontrolstrategyforcompleteanesthesiahemodynamicstabilizationinpatientsundergoingsurgicalprocedures
AT isabelarbirs anoveldecentralizeddecoupledfractionalordercontrolstrategyforcompleteanesthesiahemodynamicstabilizationinpatientsundergoingsurgicalprocedures
AT claramionescu anoveldecentralizeddecoupledfractionalordercontrolstrategyforcompleteanesthesiahemodynamicstabilizationinpatientsundergoingsurgicalprocedures
AT cristinaimuresan anoveldecentralizeddecoupledfractionalordercontrolstrategyforcompleteanesthesiahemodynamicstabilizationinpatientsundergoingsurgicalprocedures
AT erwinthegedus noveldecentralizeddecoupledfractionalordercontrolstrategyforcompleteanesthesiahemodynamicstabilizationinpatientsundergoingsurgicalprocedures
AT isabelarbirs noveldecentralizeddecoupledfractionalordercontrolstrategyforcompleteanesthesiahemodynamicstabilizationinpatientsundergoingsurgicalprocedures
AT claramionescu noveldecentralizeddecoupledfractionalordercontrolstrategyforcompleteanesthesiahemodynamicstabilizationinpatientsundergoingsurgicalprocedures
AT cristinaimuresan noveldecentralizeddecoupledfractionalordercontrolstrategyforcompleteanesthesiahemodynamicstabilizationinpatientsundergoingsurgicalprocedures