Heterogeneous catalytic reduction of substituted 5-acyl-1,3-dioxanes
Objectives. To study the hydrogenation of substituted 5-acyl-1,3-dioxanes in the presence of metal-containing catalysts (Pt/Re, Pd/C, Ni/kieselguhr, and Ni/Mo).Methods. In order to determine the qualitative and quantitative composition of the reaction masses, the following analysis methods were used...
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MIREA - Russian Technological University
2022-07-01
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| Series: | Тонкие химические технологии |
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| Online Access: | https://www.finechem-mirea.ru/jour/article/view/1837 |
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| author | A. I. Musin Yu. G. Borisova G. Z. Raskil’dina R. R. Daminev A. R. Davletshin S. S. Zlotskii |
| author_facet | A. I. Musin Yu. G. Borisova G. Z. Raskil’dina R. R. Daminev A. R. Davletshin S. S. Zlotskii |
| author_sort | A. I. Musin |
| collection | DOAJ |
| description | Objectives. To study the hydrogenation of substituted 5-acyl-1,3-dioxanes in the presence of metal-containing catalysts (Pt/Re, Pd/C, Ni/kieselguhr, and Ni/Mo).Methods. In order to determine the qualitative and quantitative composition of the reaction masses, the following analysis methods were used: gas-liquid chromatography (using the Kristall 2000 hardware complex); mass-spectroscopy (using Chromatec-Kristall 5000M device with NIST 2012); nuclear magnetic resonance (NMR) spectrometry (using Bruker AM-500 device with operating frequencies of 500 and 125 MHz).Results. Hydrogenation of substituted 5-acyl-1,3-dioxanes obtained by condensation of carbonyl compounds with paraformaldehyde and sulfuric acid was used to synthesize heterocyclic alcohols in the presence of metal-containing catalysts with a conversion of the initial ketones of 60–90% and a formation selectivity of target products of 70–90%. Substances were analyzed and confirmed by gas-liquid chromatography, mass spectrometry and NMR spectroscopy.Conclusions. The best catalyst for the reduction of substituted 5-acyl-1,3-dioxanes is Pd/C. By using this catalyst, it is possible to achieve a high selectivity for the formation of the corresponding heterocyclic alcohols at a conversion rate of the initial ketones of 60–90%. |
| format | Article |
| id | doaj-art-37e87ed355694bdc9caa90e70ea5826c |
| institution | Kabale University |
| issn | 2410-6593 2686-7575 |
| language | Russian |
| publishDate | 2022-07-01 |
| publisher | MIREA - Russian Technological University |
| record_format | Article |
| series | Тонкие химические технологии |
| spelling | doaj-art-37e87ed355694bdc9caa90e70ea5826c2025-08-20T03:56:32ZrusMIREA - Russian Technological UniversityТонкие химические технологии2410-65932686-75752022-07-0117320120910.32362/2410-6593-2022-17-3-201-2091679Heterogeneous catalytic reduction of substituted 5-acyl-1,3-dioxanesA. I. Musin0Yu. G. Borisova1G. Z. Raskil’dina2R. R. Daminev3A. R. Davletshin4S. S. Zlotskii5Institute of Chemical Technology and Engineering, Ufa State Petroleum Technological University, SterlitamakUfa State Petroleum Technological UniversityUfa State Petroleum Technological UniversityUfa State Petroleum Technological UniversityUfa State Petroleum Technological UniversityUfa State Petroleum Technological UniversityObjectives. To study the hydrogenation of substituted 5-acyl-1,3-dioxanes in the presence of metal-containing catalysts (Pt/Re, Pd/C, Ni/kieselguhr, and Ni/Mo).Methods. In order to determine the qualitative and quantitative composition of the reaction masses, the following analysis methods were used: gas-liquid chromatography (using the Kristall 2000 hardware complex); mass-spectroscopy (using Chromatec-Kristall 5000M device with NIST 2012); nuclear magnetic resonance (NMR) spectrometry (using Bruker AM-500 device with operating frequencies of 500 and 125 MHz).Results. Hydrogenation of substituted 5-acyl-1,3-dioxanes obtained by condensation of carbonyl compounds with paraformaldehyde and sulfuric acid was used to synthesize heterocyclic alcohols in the presence of metal-containing catalysts with a conversion of the initial ketones of 60–90% and a formation selectivity of target products of 70–90%. Substances were analyzed and confirmed by gas-liquid chromatography, mass spectrometry and NMR spectroscopy.Conclusions. The best catalyst for the reduction of substituted 5-acyl-1,3-dioxanes is Pd/C. By using this catalyst, it is possible to achieve a high selectivity for the formation of the corresponding heterocyclic alcohols at a conversion rate of the initial ketones of 60–90%.https://www.finechem-mirea.ru/jour/article/view/1837hydrogenation5-acyl-1,3-dioxanesheterocyclic alcoholscatalysts pt/re, pd/c, ni/kieselguhr, ni/mo |
| spellingShingle | A. I. Musin Yu. G. Borisova G. Z. Raskil’dina R. R. Daminev A. R. Davletshin S. S. Zlotskii Heterogeneous catalytic reduction of substituted 5-acyl-1,3-dioxanes Тонкие химические технологии hydrogenation 5-acyl-1,3-dioxanes heterocyclic alcohols catalysts pt/re, pd/c, ni/kieselguhr, ni/mo |
| title | Heterogeneous catalytic reduction of substituted 5-acyl-1,3-dioxanes |
| title_full | Heterogeneous catalytic reduction of substituted 5-acyl-1,3-dioxanes |
| title_fullStr | Heterogeneous catalytic reduction of substituted 5-acyl-1,3-dioxanes |
| title_full_unstemmed | Heterogeneous catalytic reduction of substituted 5-acyl-1,3-dioxanes |
| title_short | Heterogeneous catalytic reduction of substituted 5-acyl-1,3-dioxanes |
| title_sort | heterogeneous catalytic reduction of substituted 5 acyl 1 3 dioxanes |
| topic | hydrogenation 5-acyl-1,3-dioxanes heterocyclic alcohols catalysts pt/re, pd/c, ni/kieselguhr, ni/mo |
| url | https://www.finechem-mirea.ru/jour/article/view/1837 |
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