Randomised controlled trial with parallel process evaluation and health economic analysis to evaluate a nutritional management intervention, OptiCALS, for patients with amyotrophic lateral sclerosis: study protocol

Randomised controlled trial with parallel process evaluation and health economic analysis to evaluate a nutritional management intervention, OptiCALS, for patients with amyotrophic lateral sclerosis: study protocol

Introduction Amyotrophic lateral sclerosis (ALS) is a devastating illness that leads to muscle weakness and death usually within around 3 years of diagnosis. People with ALS (pwALS) often lose weight due to raised energy requirements and symptoms of the disease presenting significant challenges to t...

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Main Authors: Simon Waterhouse, Chin Maguire, Vanessa Halliday, Cindy Cooper, Elizabeth Coates, Mike Bradburn, Pamela J Shaw, Ammar Al-Chalabi, Tracey Anne Young, Christopher J McDermott, Wendy Baird, Paul Norman, Janet Cade, Sean White, Daniel Beever, Gemma Hackney, Elaine Scott, David Alexander White, Arron Peace, Shamila Ditta, Jonathan Woodward, Naseeb Ezaydi, Haris Stavroulakis
Format: Article
Language:English
Published: BMJ Publishing Group 2025-05-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/5/e096098.full
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