Spheroid assembly of mesenchymal stem cells enhances secretome-mediated corneal reinnervation and epithelial repair in a mouse model of experimental dry eye
Dry eye disease is a complex ocular surface disorder with multifactorial pathophysiology, including corneal epithelial damage, chronic inflammation, and corneal nerve dysfunction. Among these, impaired corneal innervation plays a particularly critical role, as it disrupts neurotrophic support and te...
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| Main Authors: | Shao-Wen Liu, Meng-Yu Tsai, Yang-Chun Shen, Yi-Jen Hsueh, Han Chiu, Li-Wen Hsu, Hung-Chi Chen, Chieh-Cheng Huang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2025-08-01
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| Series: | Journal of Tissue Engineering |
| Online Access: | https://doi.org/10.1177/20417314251363300 |
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