Spheroid assembly of mesenchymal stem cells enhances secretome-mediated corneal reinnervation and epithelial repair in a mouse model of experimental dry eye

Dry eye disease is a complex ocular surface disorder with multifactorial pathophysiology, including corneal epithelial damage, chronic inflammation, and corneal nerve dysfunction. Among these, impaired corneal innervation plays a particularly critical role, as it disrupts neurotrophic support and te...

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Bibliographic Details
Main Authors: Shao-Wen Liu, Meng-Yu Tsai, Yang-Chun Shen, Yi-Jen Hsueh, Han Chiu, Li-Wen Hsu, Hung-Chi Chen, Chieh-Cheng Huang
Format: Article
Language:English
Published: SAGE Publishing 2025-08-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314251363300
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