Reference-free deconvolution of complex samples based on cross-cell-type differential analysis: Systematic evaluations with various feature selection options
IntroductionGenomic and epigenomic data from complex samples reflect the average level of multiple cell types. However, differences in cell compositions can introduce bias into many relevant analyses. Consequently, the accurate estimation of cell compositions has been regarded as an important initia...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Genetics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2025.1570781/full |
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