Pharmacokinetics and brain uptake of sodium selenate and selenium in naïve rats and a lateral fluid percussion injury rat model

Pharmacokinetics and brain uptake of sodium selenate and selenium in naïve rats and a lateral fluid percussion injury rat model

Abstract Post‐traumatic epilepsy (PTE) is a life‐long complication of traumatic brain injury (TBI). The development of PTE is associated with neurological morbidity and increases the risk of mortality. An aim of EpiBioS4Rx (Epilepsy Bioinformatics Study for Antiepileptogenic Therapy) was to test pot...

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Main Authors: Chenxu Li, Pablo M. Casillas‐Espinosa, Patricia Grandizoli Saletti, Tina Chi, Glenn Yamakawa, Juliana Silva, Matt Hudson, Wei Liu, Nigel C. Jones, Sandy R. Shultz, Idrish Ali, Usha Mishra, James C. Cloyd, Solomon L. Moshe ́, Aristea S. Galanopoulou, Terence J. O'Brien, Lisa D. Coles
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Pharmacology Research & Perspectives
Subjects:
antiepileptogenesis
blood–brain barrier
pharmacokinetics
post‐traumatic epilepsy
traumatic brain injury
Online Access:https://doi.org/10.1002/prp2.1256
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