Rivaroxaban-Induced Nontraumatic Spinal Subdural Hematoma: An Uncommon Yet Life-Threatening Complication

In the last decade, the desire for safer oral anticoagulants (OACs) led to the emergence of newer drugs. Available clinical trials demonstrated a lower risk of OACs-associated life-threatening bleeding events, including intracranial hemorrhage, compared to warfarin. Nontraumatic spinal hematoma is a...

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Main Authors: Mazen Zaarour, Samer Hassan, Nishitha Thumallapally, Qun Dai
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2015/275380
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author Mazen Zaarour
Samer Hassan
Nishitha Thumallapally
Qun Dai
author_facet Mazen Zaarour
Samer Hassan
Nishitha Thumallapally
Qun Dai
author_sort Mazen Zaarour
collection DOAJ
description In the last decade, the desire for safer oral anticoagulants (OACs) led to the emergence of newer drugs. Available clinical trials demonstrated a lower risk of OACs-associated life-threatening bleeding events, including intracranial hemorrhage, compared to warfarin. Nontraumatic spinal hematoma is an uncommon yet life-threatening neurosurgical emergency that can be associated with the use of these agents. Rivaroxaban, one of the newly approved OACs, is a direct factor Xa inhibitor. To the best of our knowledge, to date, only two published cases report the incidence of rivaroxaban-induced nontraumatic spinal subdural hematoma (SSDH). Our case is the third one described and the first one to involve the cervicothoracic spine.
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series Case Reports in Hematology
spelling doaj-art-37b3548533dc46efbafa98e26bfe0a0d2025-08-20T02:07:59ZengWileyCase Reports in Hematology2090-65602090-65792015-01-01201510.1155/2015/275380275380Rivaroxaban-Induced Nontraumatic Spinal Subdural Hematoma: An Uncommon Yet Life-Threatening ComplicationMazen Zaarour0Samer Hassan1Nishitha Thumallapally2Qun Dai3Department of Medicine, Staten Island University Hospital, North Shore-LIJ Health System, Staten Island, NY 10305, USADepartment of Medicine, Division of Hematology and Oncology, Staten Island University Hospital, North Shore-LIJ Health System, Staten Island, NY 10305, USADepartment of Medicine, Staten Island University Hospital, North Shore-LIJ Health System, Staten Island, NY 10305, USADepartment of Medicine, Division of Hematology and Oncology, Staten Island University Hospital, North Shore-LIJ Health System, Staten Island, NY 10305, USAIn the last decade, the desire for safer oral anticoagulants (OACs) led to the emergence of newer drugs. Available clinical trials demonstrated a lower risk of OACs-associated life-threatening bleeding events, including intracranial hemorrhage, compared to warfarin. Nontraumatic spinal hematoma is an uncommon yet life-threatening neurosurgical emergency that can be associated with the use of these agents. Rivaroxaban, one of the newly approved OACs, is a direct factor Xa inhibitor. To the best of our knowledge, to date, only two published cases report the incidence of rivaroxaban-induced nontraumatic spinal subdural hematoma (SSDH). Our case is the third one described and the first one to involve the cervicothoracic spine.http://dx.doi.org/10.1155/2015/275380
spellingShingle Mazen Zaarour
Samer Hassan
Nishitha Thumallapally
Qun Dai
Rivaroxaban-Induced Nontraumatic Spinal Subdural Hematoma: An Uncommon Yet Life-Threatening Complication
Case Reports in Hematology
title Rivaroxaban-Induced Nontraumatic Spinal Subdural Hematoma: An Uncommon Yet Life-Threatening Complication
title_full Rivaroxaban-Induced Nontraumatic Spinal Subdural Hematoma: An Uncommon Yet Life-Threatening Complication
title_fullStr Rivaroxaban-Induced Nontraumatic Spinal Subdural Hematoma: An Uncommon Yet Life-Threatening Complication
title_full_unstemmed Rivaroxaban-Induced Nontraumatic Spinal Subdural Hematoma: An Uncommon Yet Life-Threatening Complication
title_short Rivaroxaban-Induced Nontraumatic Spinal Subdural Hematoma: An Uncommon Yet Life-Threatening Complication
title_sort rivaroxaban induced nontraumatic spinal subdural hematoma an uncommon yet life threatening complication
url http://dx.doi.org/10.1155/2015/275380
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AT nishithathumallapally rivaroxabaninducednontraumaticspinalsubduralhematomaanuncommonyetlifethreateningcomplication
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