Black Thyroid Associated with Thyroid Carcinoma
Objective. Black thyroid is a rare pigmented change seen almost exclusively in patients upon minocycline ingestion, and the process has previously been thought to be generally benign. There have been 61 reported cases of black thyroid. We are aware of 13 cases previously reported in association wit...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2010/681647 |
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| author | Emad Kandil Mohamed Abdel Khalek Haytham Alabbas Philip Daroca Tina Thethi Paul Friedlander Ryan Leblanc Obai Abdullah Bernard Jaffe Byron Crawford |
| author_facet | Emad Kandil Mohamed Abdel Khalek Haytham Alabbas Philip Daroca Tina Thethi Paul Friedlander Ryan Leblanc Obai Abdullah Bernard Jaffe Byron Crawford |
| author_sort | Emad Kandil |
| collection | DOAJ |
| description | Objective. Black thyroid is a rare pigmented change seen almost exclusively in patients upon minocycline ingestion, and the process has previously been thought to be generally benign. There have been 61 reported cases of black thyroid. We are aware of 13 cases previously reported in association with thyroid carcinoma. This paper reports six patients with black thyroid pigmentation in association with thyroid carcinoma. Design. The medical records of six patients who were diagnosed with black thyroid syndrome, all of whom underwent thyroid surgery, were reviewed. Data on age, gender, race, preoperative fine needle aspiration biopsy (FNA), thyroid function levels, and pathology reports were collected. Main Outcome. The mean age was 60 years. There were 5 females, 4 of whom were African American. All patients were clinically and biochemically euthyroid. Black pigmentation was not diagnosed in preoperative FNA, and only one patient had a preoperative diagnosis of papillary thyroid carcinoma. The other patients underwent surgery and were found to have black pigmentation of the thyroid associated with carcinoma. Conclusions. FNA does not diagnose black thyroid, which is associated with thyroid carcinoma. Thyroid glands with black pigmentation deserve thorough pathologic examination, including several sections of each specimen. |
| format | Article |
| id | doaj-art-37a27ce37aef49d4b808b6c76fbae3e9 |
| institution | DOAJ |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-37a27ce37aef49d4b808b6c76fbae3e92025-08-20T03:20:29ZengWileyInternational Journal of Endocrinology1687-83371687-83452010-01-01201010.1155/2010/681647681647Black Thyroid Associated with Thyroid CarcinomaEmad Kandil0Mohamed Abdel Khalek1Haytham Alabbas2Philip Daroca3Tina Thethi4Paul Friedlander5Ryan Leblanc6Obai Abdullah7Bernard Jaffe8Byron Crawford9Division of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USADivision of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USADivision of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USADepartment of Pathology, Tulane University School of Medicine, New Orleans, LA 70112, USADepartment of Physiology, Tulane University School of Medicine, New Orleans, LA 70112, USADivision of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USADivision of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USADivision of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USADivision of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USADepartment of Pathology, Tulane University School of Medicine, New Orleans, LA 70112, USAObjective. Black thyroid is a rare pigmented change seen almost exclusively in patients upon minocycline ingestion, and the process has previously been thought to be generally benign. There have been 61 reported cases of black thyroid. We are aware of 13 cases previously reported in association with thyroid carcinoma. This paper reports six patients with black thyroid pigmentation in association with thyroid carcinoma. Design. The medical records of six patients who were diagnosed with black thyroid syndrome, all of whom underwent thyroid surgery, were reviewed. Data on age, gender, race, preoperative fine needle aspiration biopsy (FNA), thyroid function levels, and pathology reports were collected. Main Outcome. The mean age was 60 years. There were 5 females, 4 of whom were African American. All patients were clinically and biochemically euthyroid. Black pigmentation was not diagnosed in preoperative FNA, and only one patient had a preoperative diagnosis of papillary thyroid carcinoma. The other patients underwent surgery and were found to have black pigmentation of the thyroid associated with carcinoma. Conclusions. FNA does not diagnose black thyroid, which is associated with thyroid carcinoma. Thyroid glands with black pigmentation deserve thorough pathologic examination, including several sections of each specimen.http://dx.doi.org/10.1155/2010/681647 |
| spellingShingle | Emad Kandil Mohamed Abdel Khalek Haytham Alabbas Philip Daroca Tina Thethi Paul Friedlander Ryan Leblanc Obai Abdullah Bernard Jaffe Byron Crawford Black Thyroid Associated with Thyroid Carcinoma International Journal of Endocrinology |
| title | Black Thyroid Associated with Thyroid Carcinoma |
| title_full | Black Thyroid Associated with Thyroid Carcinoma |
| title_fullStr | Black Thyroid Associated with Thyroid Carcinoma |
| title_full_unstemmed | Black Thyroid Associated with Thyroid Carcinoma |
| title_short | Black Thyroid Associated with Thyroid Carcinoma |
| title_sort | black thyroid associated with thyroid carcinoma |
| url | http://dx.doi.org/10.1155/2010/681647 |
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