Evaluation of Restless Legs syndrome and growing pains in children with familial Mediterranean f

Growing pains (GP) and restless leg syndrome (RLS) are one of the frequently seen pain syndromes of childhood. These two pain syndromes -GP and RLS- may be confused with exertional leg pain (ELP) of familial Mediterranean fever (FMF). The aim of this study was to evaluate the frequency of fulfillin...

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Main Authors: Özge Altuğ-Gücenmez, Balahan Makay, Ayla Kaçar, Erbil Ünsal
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2018-04-01
Series:The Turkish Journal of Pediatrics
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Online Access:https://turkjpediatr.org/article/view/833
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author Özge Altuğ-Gücenmez
Balahan Makay
Ayla Kaçar
Erbil Ünsal
author_facet Özge Altuğ-Gücenmez
Balahan Makay
Ayla Kaçar
Erbil Ünsal
author_sort Özge Altuğ-Gücenmez
collection DOAJ
description Growing pains (GP) and restless leg syndrome (RLS) are one of the frequently seen pain syndromes of childhood. These two pain syndromes -GP and RLS- may be confused with exertional leg pain (ELP) of familial Mediterranean fever (FMF). The aim of this study was to evaluate the frequency of fulfilling the criterion for GP and RLS among children with FMF. Sixty FMF patients and 70 healthy controls were enrolled. Clinical and demographic data of patients were recorded. A questionnaire including the symptoms of GP and RLS were applied to all participants and their parents. Twenty-seven patients (45%) had ELP. Ten FMF patients and 10 healthy children fulfilled GP criteria. There was not a significant difference between patients and controls regarding GP. Three FMF patients and 7 healthy controls fulfilled RLS criteria. There was not a significant difference between two groups regarding RLS. Two out of 27 FMF patients with ELP had RLS while one out of 33 FMF patients without ELP had RLS. Eight out of 27 FMF patients with ELP fulfilled GP criteria while two out of 33 FMF patients without ELP fulfilled GP criteria (p=0.01). There was a significant inverse correlation with FMF severity score and GP (p=0.003 and r=-0.376). There was not a significant association with FMF severity score and RLS. This study suggested that GP and RLS are not more common in pediatric FMF patients than their healthy peers.
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publishDate 2018-04-01
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spelling doaj-art-37a1aabc85134dbb859d0a61c0e548c42025-08-20T02:55:21ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212018-04-0160210.24953/turkjped.2018.02.007Evaluation of Restless Legs syndrome and growing pains in children with familial Mediterranean fÖzge Altuğ-Gücenmez0Balahan Makay1Ayla Kaçar2Erbil Ünsal3Department of Pediatrics, Division of Rheumatology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.Department of Pediatrics, Division of Rheumatology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.Department of Pediatrics, Division of Rheumatology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.Department of Pediatrics, Division of Rheumatology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey. Growing pains (GP) and restless leg syndrome (RLS) are one of the frequently seen pain syndromes of childhood. These two pain syndromes -GP and RLS- may be confused with exertional leg pain (ELP) of familial Mediterranean fever (FMF). The aim of this study was to evaluate the frequency of fulfilling the criterion for GP and RLS among children with FMF. Sixty FMF patients and 70 healthy controls were enrolled. Clinical and demographic data of patients were recorded. A questionnaire including the symptoms of GP and RLS were applied to all participants and their parents. Twenty-seven patients (45%) had ELP. Ten FMF patients and 10 healthy children fulfilled GP criteria. There was not a significant difference between patients and controls regarding GP. Three FMF patients and 7 healthy controls fulfilled RLS criteria. There was not a significant difference between two groups regarding RLS. Two out of 27 FMF patients with ELP had RLS while one out of 33 FMF patients without ELP had RLS. Eight out of 27 FMF patients with ELP fulfilled GP criteria while two out of 33 FMF patients without ELP fulfilled GP criteria (p=0.01). There was a significant inverse correlation with FMF severity score and GP (p=0.003 and r=-0.376). There was not a significant association with FMF severity score and RLS. This study suggested that GP and RLS are not more common in pediatric FMF patients than their healthy peers. https://turkjpediatr.org/article/view/833Exertional leg painfamilial Mediterranean fevergrowing painsrestless legs syndrome
spellingShingle Özge Altuğ-Gücenmez
Balahan Makay
Ayla Kaçar
Erbil Ünsal
Evaluation of Restless Legs syndrome and growing pains in children with familial Mediterranean f
The Turkish Journal of Pediatrics
Exertional leg pain
familial Mediterranean fever
growing pains
restless legs syndrome
title Evaluation of Restless Legs syndrome and growing pains in children with familial Mediterranean f
title_full Evaluation of Restless Legs syndrome and growing pains in children with familial Mediterranean f
title_fullStr Evaluation of Restless Legs syndrome and growing pains in children with familial Mediterranean f
title_full_unstemmed Evaluation of Restless Legs syndrome and growing pains in children with familial Mediterranean f
title_short Evaluation of Restless Legs syndrome and growing pains in children with familial Mediterranean f
title_sort evaluation of restless legs syndrome and growing pains in children with familial mediterranean f
topic Exertional leg pain
familial Mediterranean fever
growing pains
restless legs syndrome
url https://turkjpediatr.org/article/view/833
work_keys_str_mv AT ozgealtuggucenmez evaluationofrestlesslegssyndromeandgrowingpainsinchildrenwithfamilialmediterraneanf
AT balahanmakay evaluationofrestlesslegssyndromeandgrowingpainsinchildrenwithfamilialmediterraneanf
AT aylakacar evaluationofrestlesslegssyndromeandgrowingpainsinchildrenwithfamilialmediterraneanf
AT erbilunsal evaluationofrestlesslegssyndromeandgrowingpainsinchildrenwithfamilialmediterraneanf