Assessment of tuberculosis drug efficacy using preclinical animal models and in vitro predictive techniques

Assessment of tuberculosis drug efficacy using preclinical animal models and in vitro predictive techniques

Abstract Tuberculosis (TB) killed approximately 1.3 million people in 2022 and remains a leading cause of death from the bacteria Mycobacterium tuberculosis (M.tb); this number of deaths was surpassed only by COVID-19, caused by the SARS-CoV-2 virus. The alarming emergence of multidrug-resistant (MD...

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Bibliographic Details
Main Authors: Hazem F. M. Abdelaal, Bryan J. Berube, Brendan K. Podell, Matthew H. Harband, Hadley E. Gary, Martin Perez-Jaimes, David F. Ackart, Valerie A. Reese, Sasha E. Larsen, Tiffany Pecor, David Z. Wilkins, Tanya Parish, Sara E. Maloney-Norcross, Jeffrey B. Mecham, Anthony J. Hickey, Susan L. Baldwin, Rhea N. Coler
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:npj Antimicrobials and Resistance
Online Access:https://doi.org/10.1038/s44259-024-00066-z
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