Nonalcoholic Fatty Hepatitis: An Important Clinical Condition
The entity fatty hepatitis is defined and the literature characterizing the clinical settings in which it develops is reviewed. The pathogenesis is discussed with emphasis on the common denominators shared by the various clinical conditions with which it is associated. The roles of alcohol, obesity...
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Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
1989-01-01
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Series: | Canadian Journal of Gastroenterology |
Online Access: | http://dx.doi.org/10.1155/1989/601524 |
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Summary: | The entity fatty hepatitis is defined and the literature characterizing
the clinical settings in which it develops is reviewed. The pathogenesis is
discussed with emphasis on the common denominators shared by the various
clinical conditions with which it is associated. The roles of alcohol, obesity and
type II diabetes are stressed where inhibition of fatty acid oxidation by the liver is
the basic defect in metabolism leading to fatty change, balloon degeneration and
Mallory body formation. It is concluded that this important entity is more common
than is generally appreciated. |
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ISSN: | 0835-7900 |