<i>Lactobacillus plantarum</i>-Derived Inorganic Polyphosphate Regulates Immune Function via Inhibiting M1 Polarization and Resisting Oxidative Stress in Macrophages

<i>Lactobacillus plantarum</i>-Derived Inorganic Polyphosphate Regulates Immune Function via Inhibiting M1 Polarization and Resisting Oxidative Stress in Macrophages

Inorganic polyphosphate (PolyP) is a high-molecular-weight polymer that plays multiple roles in regulating immune responses. However, the specific anti-inflammatory mechanisms of bacteria-derived PolyP are unclear. In the present study, PolyP was extracted from <i>Lactobacillus plantarum</i...

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Bibliographic Details
Main Authors: Shuzhen Li, Aijuan Zheng, Zhimin Chen, Xiaoying Wang, Jiang Chen, Zhiheng Zou, Guohua Liu
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Antioxidants
Subjects:
inorganic polyphosphate
macrophages
oxidative stress
M1 polarization
immunomodulation
Online Access:https://www.mdpi.com/2076-3921/14/4/428
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