University proceedings. Volga region. Medical sciences
Angiosarcoma is a highly malignant soft tissue sarcoma originating from vascular endothelial cells. It can be of various localizations, its occurrence does not depend on age and gender. At the clinical level, this disease can be primary or secondary in relation to various etiologies. Depending on th...
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| Format: | Article |
| Language: | English |
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Penza State University Publishing House
2025-04-01
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| Series: | Известия высших учебных заведений. Поволжский регион: Медицинские науки |
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| author | E.V. Komarova M.G. Fedorova O.D. Derevyanchuk V.D. Markina |
| author_facet | E.V. Komarova M.G. Fedorova O.D. Derevyanchuk V.D. Markina |
| author_sort | E.V. Komarova |
| collection | DOAJ |
| description | Angiosarcoma is a highly malignant soft tissue sarcoma originating from vascular endothelial cells. It can be of various localizations, its occurrence does not depend on age and gender. At the clinical level, this disease can be primary or secondary in relation to various etiologies. Depending on the place of occurrence, there may be variants of the cellular structure. General microscopic signs of angiosarcoma include angiogenesis structures, nuclear polymorphism, hyperchromasia, increased mitotic activity, areas of necrosis. The leading diagnostic method is immunohistochemical examination. Surgery and chemotherapy are used as treatment. This article considers in more detail angiosarcomas of the skin, mammary gland, soft tissues, heart, bones. In the course of this work, an analysis of scientific literature was carried out in order to thoroughly study the microscopic structure of angiosarcomas of various localizations and the relationship of clinical manifestations with morphological features. This article aims to form a more accurate understanding of the pathogenesis of angiosarcomas. |
| format | Article |
| id | doaj-art-3798eecebd4a4a45a25f4b4301d538e6 |
| institution | OA Journals |
| issn | 2072-3032 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Penza State University Publishing House |
| record_format | Article |
| series | Известия высших учебных заведений. Поволжский регион: Медицинские науки |
| spelling | doaj-art-3798eecebd4a4a45a25f4b4301d538e62025-08-20T02:08:35ZengPenza State University Publishing HouseИзвестия высших учебных заведений. Поволжский регион: Медицинские науки2072-30322025-04-01113715310.21685/2072-3032-2025-1-11University proceedings. Volga region. Medical sciencesE.V. Komarova0M.G. Fedorova1O.D. Derevyanchuk2V.D. Markina3Penza State UniversityPenza State UniversityPenza State UniversityPenza State UniversityAngiosarcoma is a highly malignant soft tissue sarcoma originating from vascular endothelial cells. It can be of various localizations, its occurrence does not depend on age and gender. At the clinical level, this disease can be primary or secondary in relation to various etiologies. Depending on the place of occurrence, there may be variants of the cellular structure. General microscopic signs of angiosarcoma include angiogenesis structures, nuclear polymorphism, hyperchromasia, increased mitotic activity, areas of necrosis. The leading diagnostic method is immunohistochemical examination. Surgery and chemotherapy are used as treatment. This article considers in more detail angiosarcomas of the skin, mammary gland, soft tissues, heart, bones. In the course of this work, an analysis of scientific literature was carried out in order to thoroughly study the microscopic structure of angiosarcomas of various localizations and the relationship of clinical manifestations with morphological features. This article aims to form a more accurate understanding of the pathogenesis of angiosarcomas.angiosarcomamalignant tumorvesselmorphological featuresmacroscopic examinationmicroscopy |
| spellingShingle | E.V. Komarova M.G. Fedorova O.D. Derevyanchuk V.D. Markina University proceedings. Volga region. Medical sciences Известия высших учебных заведений. Поволжский регион: Медицинские науки angiosarcoma malignant tumor vessel morphological features macroscopic examination microscopy |
| title | University proceedings. Volga region. Medical sciences |
| title_full | University proceedings. Volga region. Medical sciences |
| title_fullStr | University proceedings. Volga region. Medical sciences |
| title_full_unstemmed | University proceedings. Volga region. Medical sciences |
| title_short | University proceedings. Volga region. Medical sciences |
| title_sort | university proceedings volga region medical sciences |
| topic | angiosarcoma malignant tumor vessel morphological features macroscopic examination microscopy |
| work_keys_str_mv | AT evkomarova universityproceedingsvolgaregionmedicalsciences AT mgfedorova universityproceedingsvolgaregionmedicalsciences AT odderevyanchuk universityproceedingsvolgaregionmedicalsciences AT vdmarkina universityproceedingsvolgaregionmedicalsciences |