Improving locomotor performance with motor imagery and tDCS in young adults

Abstract The study aimed to assess the feasibility and potential efficacy of a non-motor intervention utilizing motor imagery (MI) and transcranial direct current stimulation (tDCS) to enhance motor function. The research involved a double-blind, randomized, controlled trial with three groups: MIAct...

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Main Authors: Hope E Gamwell-Muscarello, Alan R. Needle, Marco Meucci, Jared W. Skinner
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-86039-2
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author Hope E Gamwell-Muscarello
Alan R. Needle
Marco Meucci
Jared W. Skinner
author_facet Hope E Gamwell-Muscarello
Alan R. Needle
Marco Meucci
Jared W. Skinner
author_sort Hope E Gamwell-Muscarello
collection DOAJ
description Abstract The study aimed to assess the feasibility and potential efficacy of a non-motor intervention utilizing motor imagery (MI) and transcranial direct current stimulation (tDCS) to enhance motor function. The research involved a double-blind, randomized, controlled trial with three groups: MIActive, MISham, and Control. Participants engaged in a cognitively demanding obstacle course, with time and prefrontal activation (ΔO2Hb and ΔHHb) measured across three-time points (Baseline, Post-test, 1-week follow-up). Following a pretest, active or sham tDCS was administered during an MI session, while the Control group did not receive this intervention. The MIActive group showed significant improvements in time-to-completion immediately after the intervention and one week later. Additionally, ΔO2Hb levels were lower in the MIActive group than in the other groups. These findings suggest that the combination of MI and tDCS could lead to motor improvements. The study outcomes support the feasibility and initial effectiveness of using MI and tDCS as a non-motor intervention to enhance motor outcomes in short and medium terms. Further research is recommended to explore the impact of this intervention in individuals with existing motor impairments. This study contributes to the growing body of evidence on the potential of non-motor interventions to induce neuroplastic changes that improve motor function. Clinical trial registration: ClinicalTrials.gov, identifier NCT06414213 16/05/2024.
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spelling doaj-art-3797df0b08ba407db691004a9ac71e0b2025-08-20T02:40:33ZengNature PortfolioScientific Reports2045-23222025-01-0115111210.1038/s41598-025-86039-2Improving locomotor performance with motor imagery and tDCS in young adultsHope E Gamwell-Muscarello0Alan R. Needle1Marco Meucci2Jared W. Skinner3Department of Public Health and Exercise Science, Appalachian State UniversityDepartment of Public Health and Exercise Science, Appalachian State UniversityDepartment of Public Health and Exercise Science, Appalachian State UniversityDepartment of Public Health and Exercise Science, Appalachian State UniversityAbstract The study aimed to assess the feasibility and potential efficacy of a non-motor intervention utilizing motor imagery (MI) and transcranial direct current stimulation (tDCS) to enhance motor function. The research involved a double-blind, randomized, controlled trial with three groups: MIActive, MISham, and Control. Participants engaged in a cognitively demanding obstacle course, with time and prefrontal activation (ΔO2Hb and ΔHHb) measured across three-time points (Baseline, Post-test, 1-week follow-up). Following a pretest, active or sham tDCS was administered during an MI session, while the Control group did not receive this intervention. The MIActive group showed significant improvements in time-to-completion immediately after the intervention and one week later. Additionally, ΔO2Hb levels were lower in the MIActive group than in the other groups. These findings suggest that the combination of MI and tDCS could lead to motor improvements. The study outcomes support the feasibility and initial effectiveness of using MI and tDCS as a non-motor intervention to enhance motor outcomes in short and medium terms. Further research is recommended to explore the impact of this intervention in individuals with existing motor impairments. This study contributes to the growing body of evidence on the potential of non-motor interventions to induce neuroplastic changes that improve motor function. Clinical trial registration: ClinicalTrials.gov, identifier NCT06414213 16/05/2024.https://doi.org/10.1038/s41598-025-86039-2Motor imageryNeuroplasticityRehabilitationtDCS
spellingShingle Hope E Gamwell-Muscarello
Alan R. Needle
Marco Meucci
Jared W. Skinner
Improving locomotor performance with motor imagery and tDCS in young adults
Scientific Reports
Motor imagery
Neuroplasticity
Rehabilitation
tDCS
title Improving locomotor performance with motor imagery and tDCS in young adults
title_full Improving locomotor performance with motor imagery and tDCS in young adults
title_fullStr Improving locomotor performance with motor imagery and tDCS in young adults
title_full_unstemmed Improving locomotor performance with motor imagery and tDCS in young adults
title_short Improving locomotor performance with motor imagery and tDCS in young adults
title_sort improving locomotor performance with motor imagery and tdcs in young adults
topic Motor imagery
Neuroplasticity
Rehabilitation
tDCS
url https://doi.org/10.1038/s41598-025-86039-2
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