Relation between Blood Pressure Variability within a Single Visit and Stroke

Blood pressure variability (BPV) has been identified as an important risk factor for cardiovascular events. The white coat effect (WCE), which is measured as the first systolic blood pressure (SBP) measurement minus the mean of the second and third measurements, is a BPV indicator within a single vi...

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Bibliographic Details
Main Authors: Wei Ma, Ying Yang, Litong Qi, Baowei Zhang, Lei Meng, Yan Zhang, Min Li, Yong Huo
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2021/2920140
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Summary:Blood pressure variability (BPV) has been identified as an important risk factor for cardiovascular events. The white coat effect (WCE), which is measured as the first systolic blood pressure (SBP) measurement minus the mean of the second and third measurements, is a BPV indicator within a single visit. In total, 2,972 participants who had three measurements of BP within a single visit were included. The participants were divided into three groups based on their WCE percentiles: Group 1 (WCE2.5-97.5, 2.5–97.5th percentiles of WCE), Group 2 (WCE2.5, 0–2.4th percentiles of WCE), and Group 3 (WCE97.5, 97.6–100th percentiles of WCE). A multiple logistic regression model was used to analyze the relationship between WCE and stroke after adjusting for cardiovascular disease risk factors. Compared with the WCE2.5-97.5 group, the OR for stroke in the WCE2.5 group was 2.78 (95% CI: 1.22, 6.36, p=0.015). After adjusting for cardiovascular factors, OR increased to 3.12 (95% CI: 1.22, 7.96, p=0.017). The OR of WCE for stroke was 0.93 (95%CI: 0.87, 0.99, p=0.036). BPV within a single visit is associated with stroke. The value and direction of the change may be important as well.
ISSN:2090-0384
2090-0392