Total Flavones of <i>Rhododendron</i> Protect Against Ischemic Cerebral Injury by Regulating the Phosphorylation of the RhoA-ROCK<sub>2</sub> Pathway via Endothelial-Derived H<sub>2</sub>S

Total Flavones of <i>Rhododendron</i> Protect Against Ischemic Cerebral Injury by Regulating the Phosphorylation of the RhoA-ROCK<sub>2</sub> Pathway via Endothelial-Derived H<sub>2</sub>S

This study aims to investigate the mechanism by which the total flavones of <i>Rhododendron</i> (TFR) protect against cerebral ischemic injury through the endothelial-derived H<sub>2</sub>S-mediated regulation of RhoA phosphorylation at the Ser188 and Rho kinase 2 (ROCK<su...

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Bibliographic Details
Main Authors:	Xiaoqing Sun, Xingyu Zhang, Yuwen Li, Jiyue Wen, Zhiwu Chen, Shuo Chen
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Series:	Current Issues in Molecular Biology
Subjects:	total flavones of <i>Rhododendron</i> H<sub>2</sub>S ischemic cerebral injury RhoA at Ser188 ROCK<sub>2</sub> at Thr436
Online Access:	https://www.mdpi.com/1467-3045/47/7/513
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